Patents by Inventor Erik M. Vogan

Erik M. Vogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANT ACTRIIB PROTEINS AND USES THEREOF
    Publication number: 20220306724
    Abstract: In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 29, 2022
    Inventors: Ravindra Kumar, Asya Grinberg, Erik M. Vogan
  • Variant ActRIIB proteins and uses thereof
    Patent number: 11267865
    Abstract: In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: March 8, 2022
    Assignee: ACCELERON PHARMA INC.
    Inventors: Ravindra Kumar, Asya Grinberg, Erik M. Vogan
  • VARIANT ACTRIIB PROTEINS AND USES THEREOF
    Publication number: 20200055919
    Abstract: In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 20, 2020
    Inventors: Ravindra Kumar, Asya Grinberg, Erik M. Vogan
  • CHARGE-ENGINEERED ANTIBODIES OR COMPOSITIONS OF PENETRATION-ENHANCED TARGETING PROTEINS AND METHODS OF USE
    Publication number: 20160031985
    Abstract: The disclosure relates to charge-engineered antibodies and penetration-enhanced targeted proteins and their uses for therapeutic treatment or therapeutics delivery.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Katherine S. Bowdish, James S. Huston, Erik M. Vogan, Heather Cooke, John Ross, Kai Lin
  • FGF-10 COMPLEXES
    Publication number: 20150307576
    Abstract: The present disclosure provides complexes comprising an FGF-10 portion and a heterologous protein or peptide, as well as methods of using such complexes.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 29, 2015
    Applicant: PERMEON BIOLOGICS, INC.
    Inventors: Katherine S. Bowdish, Erik M. Vogan, John F. Ross, Ann DeWitt
  • CELL PENETRATING COMPOSITIONS FOR DELIVERY OF INTRACELLULAR ANTIBODIES AND ANTIBODY-LIKE MOIETIES AND METHODS OF USE
    Publication number: 20150266939
    Abstract: The disclosure relates to a complex comprising a Surf+ Penetrating Polypeptide and an AAM moiety for intracellular delivery, and methods of use.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 24, 2015
    Inventors: Erik M. Vogan, Alex Franzusoff, John Edwards, Ann DeWitt
  • COMPOSITIONS OF PENETRATION-ENHANCED TARGETING PROTEINS AND METHODS OF USE
    Publication number: 20150030593
    Abstract: The disclosure relates to penetration-enhanced targeted proteins and their uses for therapeutics delivery.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 29, 2015
    Applicant: PERMEON BIOLOGICS, INC.
    Inventors: Katherine S. Bowdish, James S. Huston, Erik M. Vogan
  • FGF-10 Complexes
    Publication number: 20140271640
    Abstract: The present disclosure provides complexes comprising an FGF-10 portion and a heterologous protein or peptide, as well as methods of using such complexes.
    Type: Application
    Filed: December 6, 2013
    Publication date: September 18, 2014
    Applicant: PERMEON BIOLOGICS, INC.
    Inventors: Katherine S. Bowdish, Erik M. Vogan, John F. Ross, Ann Dewitt