Patents by Inventor Erik Martinez-Hackert

Erik Martinez-Hackert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods Of Preventing Or Treating Fatty Degeneration Of Skeletal Muscle
    Publication number: 20220362333
    Abstract: Pharmaceutical compositions comprising a selective TGF-? inhibitor, such as a TGF?RII-Fc, are provided herein to prevent, reverse, reduce the occurrence of and/or treat fatty degeneration of skeletal muscle. Additionally, the selective TGF-? inhibitors may be used to inhibit fibro-adipogenic progenitor cell (FAP) differentiation into adipocytes.
    Type: Application
    Filed: July 22, 2020
    Publication date: November 17, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventors: Erik MARTINEZ-HACKERT, Monique FLOER
  • CRYPTIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20190309039
    Abstract: The disclosure features, among other things, polypeptides comprising a Cryptic polypeptide, a functional fragment thereof, or variants of any of the foregoing. Also featured are nucleic acids encoding the polypeptides, methods for producing of the polypeptides, and a variety of diagnostic and therapeutic applications in which the polypeptides are useful. For example, the polypeptides can be used to treat a subject having a condition associated with bone loss.
    Type: Application
    Filed: April 22, 2019
    Publication date: October 10, 2019
    Inventors: Erik Martinez-Hackert, Senem Aykul
  • Cryptic polypeptides and uses thereof
    Patent number: 10323074
    Abstract: The disclosure features, among other things, polypeptides comprising a Cryptic polypeptide, a functional fragment thereof, or variants of any of the foregoing. Also featured are nucleic acids encoding the polypeptides, methods for producing of the polypeptides, and a variety of diagnostic and therapeutic applications in which the polypeptides are useful. For example, the polypeptides can be used to treat a subject having a condition associated with bone loss.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 18, 2019
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Erik Martinez-Hackert, Senem Aykul
  • CRYPTIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20180215801
    Abstract: The disclosure features, among other things, polypeptides comprising a Cryptic polypeptide, a functional fragment thereof, or variants of any of the foregoing. Also featured are nucleic acids encoding the polypeptides, methods for producing of the polypeptides, and a variety of diagnostic and therapeutic applications in which the polypeptides are useful. For example, the polypeptides can be used to treat a subject having a condition associated with bone loss.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 2, 2018
    Inventors: Erik Martinez-Hackert, Senem Aykul
  • CRYPTIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20180170987
    Abstract: The disclosure features, among other things, polypeptides comprising a Cryptic polypeptide, a functional fragment thereof, or variants of any of the foregoing. Also featured are nucleic acids encoding the polypeptides, methods for producing of the polypeptides, and a variety of diagnostic and therapeutic applications in which the polypeptides are useful. For example, the polypeptides can be used to treat a subject having a condition associated with bone loss.
    Type: Application
    Filed: December 12, 2017
    Publication date: June 21, 2018
    Inventors: Erik Martinez-Hackert, Senem Aykul
  • ACTRIIA BINDING AGENTS AND USES THEREOF
    Publication number: 20170015751
    Abstract: The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIA and uses for same.
    Type: Application
    Filed: September 30, 2016
    Publication date: January 19, 2017
    Inventors: Jasbir Seehra, Erik Martinez-Hackert
  • Actriia binding agents and uses thereof
    Patent number: 9493556
    Abstract: The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIA and uses for same.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: November 15, 2016
    Assignee: Acceleron Pharma Inc.
    Inventors: Jasbir Seehra, Erik Martinez-Hackert
  • ACTRIIA BINDING AGENTS AND USES THEREOF
    Publication number: 20140199317
    Abstract: The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIA and uses for same.
    Type: Application
    Filed: January 24, 2014
    Publication date: July 17, 2014
    Applicant: ACCELERON PHARMA, INC.
    Inventors: Jasbir Seehra, Erik Martinez-Hackert
  • ACTRIIA BINDING AGENTS AND USES THEREOF
    Publication number: 20120121576
    Abstract: The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIA and uses for same.
    Type: Application
    Filed: November 8, 2011
    Publication date: May 17, 2012
    Inventors: Jasbir Seehra, Erik Martinez-Hackert