Abstract: The present invention specifically relates to a mixing and injection device for mixing, handling and injecting of biomaterials, such as ceramic biomaterials, PMMA and other materials intended for stabilising and healing fractures and lesions, and for filling voids in orthopaedic, spinal, cranio-maxillofacial, distal radius, tibia plateau or other applications where natural or artificial substances are to be delivered to such fractures, lesions or voids in the skeleton.

Abstract: Methods, systems, and sub-systems, for processing at least one chemical reaction, including one or more of constructing at least one chemical reaction query, searching at least one database using the at least one chemical reaction query, receiving at least one hit from the at least one database in response to the at least one chemical reaction query, selecting at least one desired hit from the at least one hit, creating the at least one chemical reaction using the at least one desired hit as a template, conducting the at least one chemical reaction using a reaction apparatus, and documenting at least one result of the at least one chemical reaction.

Abstract: The invention provides methods, PCR primers, sequence determination oligonucleotides, isolated polynucleotides, and kits for determining a human's capacity to metabolize a substrate of the CYP2C19 enzyme using genetic analysis.

Abstract: The invention provides methods, PCR primers, sequence determination oligonucleotides, and kits for predicting a human's capacity to metabolize a substrate of the CYP2D6 enzyme using genetic analysis.

Abstract: The invention provides oligonucleotide primer pairs, sequence determination oligonucleotides, and kits for amplification and detection of novel single nucleotide polymorphisms in the 5′ flanking regions of the CYP3A4 and CYP2C9 genes.