Patents by Inventor Erik P. Johnson
Erik P. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230143248Abstract: Described herein are methods for direct detection of microbial agent(s) in a polymicrobial sample, such as a biological sample from a human, without culturing the microbial agent(s). The direct detection can identify mixtures of bacteria and/or fungi in the sample. Also described are primer sequences and amplification techniques for performing the direct detection methods.Type: ApplicationFiled: August 22, 2022Publication date: May 11, 2023Applicant: Quest Diagnostics Investments LLCInventors: Erik P. Johnson, Nik Isely, Jamie L. Platt, Martin Siaw, Ron M. Kagen, Dale A. Schwab
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Patent number: 11421285Abstract: Described herein are methods for direct detection of microbial agent(s) in a polymicrobial sample, such as a biological sample from a human, without culturing the microbial agent(s). The direct detection can identify mixtures of bacteria and/or fungi in the sample. Also described are primer sequences and amplification techniques for performing the direct detection methods.Type: GrantFiled: June 4, 2015Date of Patent: August 23, 2022Assignee: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Nik Isely, Jamie L. Platt, Martin Siaw, Ron M. Kagen, Dale A. Schwab
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Publication number: 20220145367Abstract: The present disclosure provides methods for determining whether a patient exhibiting pneumonia-like symptoms will benefit from treatment with therapeutic agents that inhibit Legionella sp. These methods are based on detecting Legionella sp. and/or Legionella pneumophila in a biological sample. Kits for use in practicing the methods are also provided.Type: ApplicationFiled: January 30, 2020Publication date: May 12, 2022Applicant: Quest Diagnostics Investments LLCInventor: Erik P. Johnson
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Publication number: 20210363569Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: ApplicationFiled: June 7, 2021Publication date: November 25, 2021Applicant: Quest Diagnostics Investments LLCInventors: Erik P. Johnson, Dale A. Schwab
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Patent number: 11028450Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: GrantFiled: October 31, 2016Date of Patent: June 8, 2021Assignee: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Dale A. Schwab
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Publication number: 20210164022Abstract: The present invention provides methods and compositions for determining the presence and/or amount of pathogenic Leptospira in a test sample. In particular, substantially purified oligonucleotide primers and probes are described that can be used for qualitatively and quantitatively detecting pathogenic Leptospira nucleic acid in a test sample by amplification methods. The present invention also provides primers and probes for generating and detecting control nucleic acid sequences that provide a convenient method for assessing internal quality control of the Leptospira assay.Type: ApplicationFiled: January 21, 2021Publication date: June 3, 2021Applicant: Quest Diagnostics Investments LLCInventor: Erik P. JOHNSON
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Patent number: 10907218Abstract: The present invention provides methods and compositions for determining the presence and/or amount of pathogenic Leptospira in a test sample. In particular, substantially purified oligonucleotide primers and probes are described that can be used for qualitatively and quantitatively detecting pathogenic Leptospira nucleic acid in a test sample by amplification methods. The present invention also provides primers and probes for generating and detecting control nucleic acid sequences that provide a convenient method for assessing internal quality control of the Leptospira assay.Type: GrantFiled: April 4, 2016Date of Patent: February 2, 2021Assignee: Quest Diagnostics Investments LLCInventor: Erik P. Johnson
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Publication number: 20190085376Abstract: The present invention provides methods and compositions for determining the presence and/or amount of pathogenic Leptospira in a test sample. In particular, substantially purified oligonucleotide primers and probes are described that can be used for qualitatively and quantitatively detecting pathogenic Leptospira nucleic acid in a test sample by amplification methods. The present invention also provides primers and probes for generating and detecting control nucleic acid sequences that provide a convenient method for assessing internal quality control of the Leptospira assay.Type: ApplicationFiled: April 4, 2016Publication date: March 21, 2019Applicant: Quest Diagnostics Investiments LLCInventor: Erik P. Johnson
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Publication number: 20170191116Abstract: Described herein are methods for direct detection of microbial agent(s) in a polymicrobial sample, such as a biological sample from a human, without culturing the microbial agent(s). The direct detection can identify mixtures of bacteria and/or fungi in the sample. Also described are primer sequences and amplification techniques for performing the direct detection methods.Type: ApplicationFiled: June 4, 2015Publication date: July 6, 2017Applicant: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Nik Isely, Jamie L. Platt, Martin Siaw, Ron M. Kagen, Dale A. Schwab
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Publication number: 20170137867Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: ApplicationFiled: October 31, 2016Publication date: May 18, 2017Applicant: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Dale A. Schwab
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Patent number: 9481914Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: GrantFiled: October 30, 2015Date of Patent: November 1, 2016Assignee: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Dale A. Schwab
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Publication number: 20160130638Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: ApplicationFiled: October 30, 2015Publication date: May 12, 2016Applicant: Quest Diagnostics Investments IncorporatedInventors: Erik P. Johnson, Dale A. Schwab
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Patent number: 9200331Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: GrantFiled: November 17, 2010Date of Patent: December 1, 2015Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Erik P. Johnson, Dale A. Schwab
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Publication number: 20120264126Abstract: The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.Type: ApplicationFiled: November 17, 2010Publication date: October 18, 2012Applicant: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Erik P. Johnson, Dale A. Schwab