Patents by Inventor Erik Patzelt

Erik Patzelt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies specific for CD44v6
    Patent number: 7417127
    Abstract: The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: August 26, 2008
    Assignees: Boehringer Ingelheim Pharmaceuticals, Inc., Bohringer Ingelheim International GmbH
    Inventors: Gunther Adolf, Elinborg Ostermann, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider, John J. Miglietta, Augustinus Antonius Maria Silvester Van Dongen
  • Cytotoxic CD44 antibody immunoconjugates
    Patent number: 7361347
    Abstract: The invention relates to novel conjugates of CD44 antibodies with cytotoxic compounds, pharmaceutical compositions comprising such compounds, and their use in tumor therapy.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: April 22, 2008
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Guenther Adolf, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider
  • Cytotoxic CD44 antibody immunoconjugates
    Publication number: 20050271672
    Abstract: The invention relates to novel conjugates of CD44 antibodies with cytotoxic compounds, pharmaceutical compositions comprising such compounds, and their use in tumor therapy.
    Type: Application
    Filed: July 1, 2005
    Publication date: December 8, 2005
    Inventors: Guenther Adolf, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider
  • Antibodies specific for CD44v6
    Patent number: 6972324
    Abstract: The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: December 6, 2005
    Assignees: Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim International, GmbH
    Inventors: Günther Adolf, Elinborg Ostermann, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider, John J. Miglietta, Augustinus Antonius Maria Silvester Van Dongen
  • Antibodies specific for CD44v6
    Publication number: 20050214212
    Abstract: The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
    Type: Application
    Filed: May 25, 2005
    Publication date: September 29, 2005
    Inventors: Gunther Adolf, Elinborg Ostermann, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider, John Miglietta, Augustinus Antonius Van Dongen
  • FAP-activated anti-tumor prodrugs
    Publication number: 20040033957
    Abstract: The present invention relates to prodrugs which are capable of being converted into prodrug intermediates of a cytotoxic or cytostatic drug, by the catalytic action of FAP&agr;, said prodrugs exhibit
    Type: Application
    Filed: May 6, 2003
    Publication date: February 19, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Erik Patzelt, John Edward Park, Stefan Peters
  • Antibodies specific for CD44v6
    Publication number: 20030190319
    Abstract: The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
    Type: Application
    Filed: May 20, 2002
    Publication date: October 9, 2003
    Inventors: Gunther Adolf, Elinborg Ostermann, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider, John J. Miglietta, Augustinus Antonius Maria Silvester Van Dongen
  • Cytotoxic CD44 antibody immunoconjugates
    Publication number: 20030103985
    Abstract: The invention relates to novel conjugates of CD44 antibodies with cytotoxic compounds, pharmaceutical compositions comprising such compounds, and their use in tumor therapy.
    Type: Application
    Filed: May 17, 2002
    Publication date: June 5, 2003
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Guenther Adolf, Erik Patzelt, Marlies Sproll, Karl-Heinz Heider
  • Monoclonal antibody against CD44v6
    Patent number: 5916561
    Abstract: The invention concerns an antibody active against an epitope coded by the exon v6 variant of the CD44 gene. The antibody concerned has characteristics superior to those of prior art antibodies and is suitable for use in therapy and diagnosis.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: June 29, 1999
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Gunther R. Adolf, Erik Patzelt