Patents by Inventor Erik R. Remaut

Erik R. Remaut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a cytokine-producing lactococcus strain to treat colitis
    Patent number: 6746671
    Abstract: An administration strategy for the delivery at the intestinal mucosa of cytokines or cytokine antagonists, preferably of acid sensitive anti-inflammatory agents, for example, IL10 and/or soluble TNF receptor via the oral route. Preferably, inoculation occurs along with a suspension of recombinant Lactococcus lactis cells, which had been engineered to produce the respective proteins.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: June 8, 2004
    Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW
    Inventors: Lothar Steidler, Erik R. Remaut, Walter Fiers
  • Use of a cytokine-producing lactococcus strain to treat colitis
    Publication number: 20020019043
    Abstract: An administration strategy for the delivery at the intestinal mucosa of cytokines or cytokine antagonists, preferably of acid sensitive anti-inflammatory agents, such as IL10 and/or soluble TNF receptor via the oral route. Preferably, inoculation occurs along with a suspension of recombinant Lactococcus lactis cells, which had been engineered to produce the respective proteins.
    Type: Application
    Filed: April 19, 2001
    Publication date: February 14, 2002
    Inventors: Lothar Steidler, Erik R. Remaut, Walter Fiers
  • Vectors and methods for making such vectors and for expressing cloned genes
    Patent number: 5401642
    Abstract: Improved vectors and methods for expressing cloned genes of prokaryotic or eukaryotic origin and methods of making such vectors are disclosed, the improved vectors comprising promoters and operators from .lambda. phages and preferably do not include an active cro gene or an active N gene, the vectors having at least one endonuclease recognition site for cloning desired genes less than about 300 base pairs from the promoters and operators and being useful, as are methods utilizing the vectors, in producing a wide variety of prokaryotic, eukaryotic and vital polypeptides, hormones, enzymes, antigens, proteins and amino acids.
    Type: Grant
    Filed: May 7, 1993
    Date of Patent: March 28, 1995
    Assignee: Biogen, Inc.
    Inventors: Walter C. Fiers, Erik R. Remaut
  • Vectors and methods for making such vectors and for expressing cloned genes
    Patent number: 5401658
    Abstract: Improved vectors and methods for expressing cloned genes of prokaryotic or eukaryotic origin and methods of making such vectors are disclosed, the improved vectors comprising promoters and operators from .lambda. phages and preferably do not include an active cro gene or an active N gene, the vectors having at least one endonuclease recognition site for cloning desired genes less than about 300 base pairs from the promoters and operators and being useful, as are methods utilizing the vectors, in producing a wide variety of prokaryotic, eukaryotic and vital polypeptides, hormones, enzymes, antigens, proteins and amino acids.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: March 28, 1995
    Assignee: Biogen, Inc.
    Inventors: Walter C. Fiers, Erik R. Remaut