Patents by Inventor Erik S. Knudsen

Erik S. Knudsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of predicting resistance or sensitivity to therapies for cancer
    Patent number: 8470534
    Abstract: The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The methods include: a) determining the level of expression of plurality of genes regulated by retinoblastoma tumor supressor (RB) in the individual, and b) comparing the level of expression of the plurality of genes regulated by RB in the individual with a level of expression of the plurality of genes regulated by RB in a control. The application is also directed to an RNA expression profile for the loss of RB.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: June 25, 2013
    Inventors: Erik S. Knudsen, Emily E. Bosco
  • Methods of Predicting Resistance or Sensitivity to Therapies for Cancer
    Publication number: 20090149333
    Abstract: The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The methods include: a) determining the level of expression of plurality of genes regulated by retinoblastoma tumor supressor (RB) in the individual, and b) comparing the level of expression of the plurality of genes regulated by RB in the individual with a level of expression of the plurality of genes regulated by RB in a control. The application is also directed to an RNA expression profile for the loss of RB.
    Type: Application
    Filed: December 3, 2007
    Publication date: June 11, 2009
    Inventors: Erik S. Knudsen, Emily E. Bosco