Patents by Inventor Erik Sallomons

Erik Sallomons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for providing sialylated oligosaccharides
    Patent number: 9539270
    Abstract: The invention relates to a method for providing analogs of human milk oligosaccharides (HMO), in particular oligosaccharides containing terminal sialic acid. The method comprises the steps of: a) providing a source of non-digestible galactooligosaccharides (GOS) containing at least two terminally bonded ?-linked galactose residues; b) providing a sialic acid donor having (?2-3)-sialylated O-glycans; c) contacting said GOS with said sialic acid donor in the presence of an enzyme having trans-sialidase activity in an enzyme reaction mixture; and d) isolating from said enzyme reaction mixture a fraction comprising at least 20 percent by weight of disialylated galactooligosaccharides (di-Sia-GOS) based on the dry matter.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: January 10, 2017
    Assignee: RIJKSUNIVERSITEIT GRONINGEN
    Inventors: Erik Sallomons, Maarten Hotse Wilbrink, Peter Sanders, Johannis Paulus Kamerling, Catherina Anna van Vuure, Johannes Adrianus Hage
  • METHODS FOR PROVIDING SIALYLATED OLIGOSACCHARIDES
    Publication number: 20140336140
    Abstract: The invention relates to a method for providing analogs of human milk oligosaccharides (HMO), in particular oligosaccharides containing terminal sialic acid. The method comprises the steps of: a) providing a source of non-digestible galactooligosaccharides (GOS) containing at least two terminally bonded ?-linked galactose residues; b) providing a sialic acid donor having (?2-3)-sialylated O-glycans; c) contacting said GOS with said sialic acid donor in the presence of an enzyme having trans-sialidase activity in an enzyme reaction mixture; and d) isolating from said enzyme reaction mixture a fraction comprising at least 20 percent by weight of disialylated galactooligosaccharides (di-Sia-GOS) based on the dry matter.
    Type: Application
    Filed: December 6, 2012
    Publication date: November 13, 2014
    Inventors: Erik Sallomons, Maarten Hotse Wilbrink, Peter Sanders, Johannis Paulis Kamerling, Catherina Anna van Vuure, Johannes Adrianus Hage