Patents by Inventor Erik Stephen Espling

Erik Stephen Espling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATERIALS AND METHODS FOR IMPROVED IMMUNOGLYCOPROTEINS
    Publication number: 20130323233
    Abstract: Immunoglycoproteins, including antibodies, with improved ADCC and altered glycosylation patterns are provided. Also provided are cell culturing methods and media for producing such immunoglycoproteins, and therapeutic uses of such immunoglycoproteins.
    Type: Application
    Filed: December 21, 2012
    Publication date: December 5, 2013
    Inventors: Erik Stephen ESPLING, Peter Armstrong Thompson, Peter Robert Baum
  • Materials and Methods for Improved Immunoglycoproteins
    Publication number: 20130280240
    Abstract: Immunoglycoproteins, including antibodies, with improved ADCC and altered glycosylation patterns arc provided. Also provided are cell culturing methods and media for producing such immunoglycoproteins, and therapeutic uses of such immunoglycoproteins.
    Type: Application
    Filed: June 14, 2013
    Publication date: October 24, 2013
    Inventors: Peter Robert Baum, Erik Stephen Espling, Peter Armstrong Thompson
  • Materials and methods for improved immunoglycoproteins
    Patent number: 7846434
    Abstract: Immunoglycoproteins, including antibodies, with improved ADCC and altered glycosylation patterns are provided. Also provided are cell culturing methods and media for producing such immunoglycoproteins, and therapeutic uses of such immunoglycoproteins.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: December 7, 2010
    Assignee: Trubion Pharmaceuticals, Inc.
    Inventors: Erik Stephen Espling, Peter Armstrong Thompson, Peter Robert Baum
  • MATERIALS AND METHODS FOR IMPROVED IMMUNOGLYCOPROTEINS
    Publication number: 20100150948
    Abstract: Immunoglycoproteins, including antibodies, with improved ADCC and altered glycosylation patterns are provided. Also provided are cell culturing methods and media for producing such immunoglycoproteins, and therapeutic uses of such immuno-glycoproteins.
    Type: Application
    Filed: October 24, 2007
    Publication date: June 17, 2010
    Applicant: TRUBION PHARMACEUTICALS, INC.
    Inventors: Peter Robert Baum, Erik Stephen Espling, Peter Armstrong Thompson
  • BINDING PROTEINS COMPRISING IMMUNOGLOBULIN HINGE AND FC REGIONS HAVING ALTERED FC EFFECTOR FUNCTIONS
    Publication number: 20080227958
    Abstract: Provided herein are binding proteins comprising one or more immunoglobulin Fc region hinge, CH2, and/or CH3 domain wherein one or more hinge and/or constant region CH2 and/or CH3 domain is modified to alter the binding protein's binding affinity and/or specificity for a cognate receptor (e.g., an Fc receptor) and/or to impart one or more new binding specificity(ies) to the hinge and/or constant region that the corresponding unmodified immunoglobulin does not possess (e.g., affinity for distinct class of cognate receptor distinct from the class of cognate receptor to which the unmodified binding protein specifically binds). Binding proteins according to the present invention include, for example, modified antibodies, antibody fragments, recombinant binding proteins, and molecularly engineered binding domain-immunoglobulin fusion proteins, including small modular immunopharmaceutical products (SMIP™ products).
    Type: Application
    Filed: April 13, 2007
    Publication date: September 18, 2008
    Applicant: Trubion Pharmaceuticals Inc.
    Inventors: Peter Armstrong Thompson, Erik Stephen Espling, Peter Robert Baum, Phillip Tan