Abstract: A bioprinter (1) comprising at least one printhead (4a, 4b, 4c) with nozzle (5), a printbed (20) onto which the printhead (4a, 4b, 4c) is arranged to print an ink, an ultrasonic sensor arrangement arranged at the printbed (20), a controller (7) arranged to control movement of the printhead/nozzle (4a, 4b, 4c; 5) and to perform calibration of the printhead/nozzle (4a, 4b, 5 4c; 5) based on information from the ultrasonic sensor arrangement.

Abstract: The present disclosure relates to a 3D bioprinter (1) comprising a base unit (2). The base unit (2) has a support (3) adapted for mounting of at least one toolhead (4), a communication interface part (5) for communication of data with the at least one toolhead (4), when mounted, and a base unit processing element (7) adapted to communicate with a toolhead processing element (8) of the at least one toolhead over said communication interface part (5). The present disclosure relates further to a 3D bioprinter toolhead. The present disclosure relates further to a method for bioprinting a construct.

Abstract: The present disclosure relates to a 3D printer (1) for 3D printing of a construct. The 3D printer (1) has a print bed (2). The 3D printer further comprises at least one actuating tool head (3) with an extrusion element (4), wherein the extrusion element and the print bed are movable in relation to each other. The 3D printer also comprises at least one sensor (5) arranged to sense a force applied to the print bed (2) by the extrusion element (4), or vice versa. The 3D printer additionally comprises a control element (7) arranged to detect when the sensed force exceeds a predetermined value and to record a position of the print bed or extrusion element related to the detection that the predetermined value is exceeded. The present disclosure also relates to corresponding methods and computer programs.

Abstract: The present disclosure relates to the field of liquid handling and dispensing systems in combination with additive manufacturing. In particular, it relates to temperature-controlled units, i.e. dispensing heads and source well holders, for receiving, holding and releasing liquid and semi-liquid material, liquid-handling and dispensing systems, apparatuses and methods for applying temperature-sensitive liquids. A temperature-controlled unit (1) comprises at least one Peltier element (3), each Peltier element having opposite first and second surfaces (4a, 4b). The unit (1) further comprises at least one cooling element (5). The at least one Peltier element (3) is arranged to have each respective first surface (4a) facing a reservoir block (2) of the unit (1). The at least one cooling element (5) is thermally connected to the Peltier element (3) and arranged to transfer heat generated by the at least one Peltier element (3) and dissipate the transferred heat away from the at least one Peltier element (3).

Abstract: The present disclosure relates to a print bed (1) for regulating a temperature of the print bed (1). The print bed (1) comprises at least one Peltier element (2), each Peltier element having opposite first and a second surfaces (3a, 3b). The print bed (1) further comprises at least one heatsink (4). The at least one Peltier element (2) is arranged to have each respective first surface (3a) facing a print surface (5) of the print bed (1). The at least one heatsink (4) is thermally connected to the Peltier element (2) and arranged to transfer heat generated by the at least one Peltier element (2) and dissipate the transferred heat away from the at least one Peltier element (2). The present disclosure further relates to corresponding 3D-printers, methods, computer programs and modules.

Abstract: The present disclosure relates to a 3D bioprinter (1) comprising a base unit (2). The base unit (2) has a support (3) adapted for mounting of at least one toolhead (4), a communication interface part (5) for communication of data with the at least one toolhead (4), when mounted, and a base unit processing element (7) adapted to communicate with a toolhead processing element (8) of the at least one toolhead over said communication interface part (5). The present disclosure relates further to a 3D bioprinter toolhead.

Abstract: The present disclosure relates to a print bed (1) for regulating a temperature of the print bed (1). The print bed (1) comprises at least one Peltier element (2), each Peltier element having opposite first and a second surfaces (3a, 3b). The print bed (1) further comprises at least one heatsink (4). The at least one Peltier element (2) is arranged to have each respective first surface (3a) facing a print surface (5) of the print bed (1). The at least one heatsink (4) is thermally connected to the Peltier element (2) and arranged to transfer heat generated by the at least one Peltier element (2) and dissipate the transferred heat away from the at least one Peltier element (2). The present disclosure further relates to corresponding 3D-printers, methods, computer programs and modules.

Abstract: The present disclosure relates to a 3D printer (1) for 3D printing of a construct. The 3D printer (1) has a print bed (2). The 3D printer further comprises at least one actuating tool head (3) with an extrusion element (4), wherein the extrusion element and the print bed are movable in relation to each other. The 3D printer also comprises at least one sensor (5) arranged to sense a force applied to the print bed (2) by the extrusion element (4), or vice versa. The 3D printer additionally comprises a control element (7) arranged to detect when the sensed force exceeds a predetermined value and to record a position of the print bed or extrusion element related to the detection that the predetermined value is exceeded. The present disclosure also relates to corresponding methods and computer programs.