Patents by Inventor Erik STOOPS

Erik STOOPS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alpha-synuclein binding antibodies, or antigen binding portions thereof
    Patent number: 12459998
    Abstract: The present invention relates to an isolated antibody, or antigen-binding portion thereof, with a higher binding affinity to alpha-synuclein oligomers compared to alpha-synuclein fibrils and/or alpha-synuclein monomers. The invention further describes in vitro and/or ex vivo methods using the isolated antibody, or antigen-binding portion thereof, to detect alpha-synuclein oligomers. The invention further provides a treatment-option for synucleinopathies, or provide a method to diagnose synucleinopathies.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: November 4, 2025
    Assignee: SYNGLE THERAPEUTICS B.V.
    Inventors: Augustinus Petrus Henricus Scheefhals, Wilbrandt Jannes Wichert Tepper, Erik Stoops
  • NOVEL ALPHA-SYNUCLEIN BINDING ANTIBODIES, OR ANTIGEN BINDING PORTIONS THEREOF
    Publication number: 20230151089
    Abstract: The present invention relates to an isolated antibody, or antigen-binding portion thereof, with a higher binding affinity to alpha-synuclein oligomers compared to alpha-synuclein fibrils and/or alpha-synuclein monomers. The invention further describes in vitro and/or ex vivo methods using the isolated antibody, or antigen-binding portion thereof, to detect alpha-synuclein oligomers. The invention further provides a treatment-option for synucleinopathies, or provide a method to diagnose synucleinopathies.
    Type: Application
    Filed: April 12, 2021
    Publication date: May 18, 2023
    Inventors: Augustinus Petrus Henricus SCHEEFHALS, Wilbrandt Jannes Wichert TEPPER, Erik STOOPS