Patents by Inventor Erik Uwe Arango Gutierrez

Erik Uwe Arango Gutierrez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucose oxidase variants and methods of using the same
    Patent number: 9926536
    Abstract: Novel glucose oxidase (GOx) variants are disclosed that have the substitutions of T30V and I94V set forth in SEQ ID NO:1, and additionally at least one further amino acid substitution in the enzyme sequence in any of the positions S53; A137; A173; A332; F414 and V560. The GOx variants herein exhibit specificity for glucose and significantly reduced oxygen consumption rates and/or increased enzyme activity for electron mediators other than oxygen. Also provided are assay devices incorporating at least one of the GOx variants herein for improved blood glucose measurements.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: March 27, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Marco Bocola, Hartmut Duefel, Erik Uwe Arango Gutierrez, Dieter Heindl, Thomas Meier, Hemanshu Mundhada, Ulrich Schwaneberg, Michael Tacke