Abstract: A neutral electrode (12) is formed on the patient (11) in that an electrically conductible mass that can solidify is applied on the skin of the patient (11). An electrically conductible inlay (17) can be arranged on or embedded in the forming electrode body (16) prior, during or after the application of the mass, the inlay (17) is or can be connected with the neutral electrode connection cable (13). The inlay (17) serves to electrically contact the electrode body (16) in a large area that in turn establishes a reliable electrical contact to the patient (11).

Abstract: Methods for purifying biological macromolecules are provided. Aspects of the subject methods include contacting the biological macromolecule with an exemplary hydroxamate affinity tag to produce a tagged moiety followed by purification of the tagged moiety by immobilized metal affinity chromatography (IMAC). Also provided are kits comprising an exemplary subject hydroxamate affinity tag, an IMAC resin and a metal ion configured for loading onto the resin, wherein the metal ion is capable of binding to a compound containing the hydroxamate affinity tag.

Abstract: A neutral electrode (12) is formed on the patient (11) in that an electrically conductible mass that can solidify is applied on the skin of the patient (11). An electrically conductible inlay (17) can be arranged on or embedded in the forming electrode body (16) prior, during or after the application of the mass, the inlay (17) is or can be connected with the neutral electrode connection cable (13). The inlay (17) serves to electrically contact the electrode body (16) in a large area that in turn establishes a reliable electrical contact to the patient (11).

Abstract: Methods for the treatment of type 2 diabetes and related conditions comprising the admini-stration of balaglitazone in combination with one or more other antidiabetic compound is pro-vided together with combinations useful in said treatment.