Patents by Inventor Erika McAfee

Erika McAfee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20240052311
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: October 27, 2023
    Publication date: February 15, 2024
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20240018473
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: September 22, 2023
    Publication date: January 18, 2024
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • CELL CONCENTRATION METHODS AND DEVICES FOR USE IN AUTOMATED BIOREACTORS
    Publication number: 20230407234
    Abstract: The present disclosure provides cassettes for use in automated cell engineering systems that include cell concentration filters for reducing fluid volume of a cell sample during or following automated processing. The disclosure also provides methods of concentrating a cell population, as well as automated cell engineering systems that can utilize the cassettes and carry out the methods.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 21, 2023
    Inventors: Joseph O'CONNOR, Erika MCAFEE, Samatha BANDAPALLE, Yaling SHI, Eytan ABRAHAM
  • End-to-end cell therapy automation
    Patent number: 11827902
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: November 28, 2023
    Assignees: LONZA WALKERSVILLE, INC., LONZA COLOGNE GMBH, OCTANE BIOTECH INC.
    Inventors: Yaling Shi, Erika McAfee, Samatha Bandapalle, Ann Siehoff, Timo Gleissner, Joseph O'Connor, Eytan Abraham, Kelly Purpura, Nuala Trainor, Timothy Smith
  • End-to-end cell therapy automation
    Patent number: 11781113
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: October 10, 2023
    Assignees: LONZA WALKERSVILLE, INC., LONZA COLOGNE GMBH, OCTANE BIOTECH INC.
    Inventors: Yaling Shi, Erika McAfee, Samatha Bandapalle, Ann Siehoff, Timo Gleissner, Joseph O'Connor, Eytan Abraham, Kelly Purpura, Nuala Trainor, Timothy Smith
  • Cell concentration methods and devices for use in automated bioreactors
    Patent number: 11773365
    Abstract: The present disclosure provides cassettes for use in automated cell engineering systems that include cell concentration filters for reducing fluid volume of a cell sample during or following automated processing. The disclosure also provides methods of concentrating a cell population, as well as automated cell engineering systems that can utilize the cassettes and carry out the methods.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: October 3, 2023
    Assignee: LONZA WALKERSVILLE, INC.
    Inventors: Joseph O'Connor, Erika McAfee, Samatha Bandapalle, Yaling Shi, Eytan Abraham
  • End-to-end cell therapy automation
    Patent number: 11447745
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: September 20, 2022
    Assignees: LONZA WALKERSVILLE, INC., LONZA COLOGNE GMBH, OCTANE BIOTECH INC.
    Inventors: Yaling Shi, Erika McAfee, Samatha Bandapalle, Ann Siehoff, Timo Gleissner, Joseph O'Connor, Eytan Abraham, Kelly Purpura, Nuala Trainor, Timothy Smith
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20220282212
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 8, 2022
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20220282213
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 8, 2022
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20220282214
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 8, 2022
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • CELL ISOLATION FOR USE IN AUTOMATED BIOREACTORS
    Publication number: 20220267712
    Abstract: The present disclosure provides cassettes for use in automated cell engineering systems that include cell separation filters for capturing a target cell population for automated processing. The disclosure also provides methods of separating a target cell population, as well as automated cell engineering systems using the cassettes and for carrying out the methods.
    Type: Application
    Filed: April 28, 2022
    Publication date: August 25, 2022
    Inventors: Erika MCAFEE, Yaling SHI, Samatha BANDAPALLE, Eytan ABRAHAM
  • End-to-end cell therapy automation
    Patent number: 11371018
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: June 28, 2022
    Assignees: OCTANE BIOTECH INC., LONZA WALKERSVILLE, INC., LONZA COLOGNE GMBH
    Inventors: Yaling Shi, Erika McAfee, Samatha Bandapalle, Ann Siehoff, Timo Gleissner, Joseph O'Connor, Eytan Abraham, Kelly Purpura, Nuala Trainor, Timothy Smith
  • CELL CONCENTRATION METHODS AND DEVICES FOR USE IN AUTOMATED BIOREACTORS
    Publication number: 20200255793
    Abstract: The present disclosure provides cassettes for use in automated cell engineering systems that include cell concentration filters for reducing fluid volume of a cell sample during or following automated processing. The disclosure also provides methods of concentrating a cell population, as well as automated cell engineering systems that can utilize the cassettes and carry out the methods.
    Type: Application
    Filed: February 5, 2020
    Publication date: August 13, 2020
    Inventors: Joseph O'CONNOR, Erika MCAFEE, Samatha BANDAPALLE, Yaling SHI, Eytan ABRAHAM
  • BEDSIDE AUTOMATED CELL ENGINEERING SYSTEM AND METHODS
    Publication number: 20200179582
    Abstract: The present disclosure provides cell therapy production systems that can suitably be used in a patient bedside setting. Such systems allow for direct removal of a patient's blood, automated processing to produce a cell therapy, and then infusion back into the patient, without the need to remove the system from the patient's bedside. Also provided herein are systems for production of cell therapies in a bedside setting.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 11, 2020
    Inventors: Erika MCAFEE, Yaling SHI, Samatha BANDAPALLE, Eytan ABRAHAM, Phil DENSHAM, Raelyn DANIELS, Nuala TRAINOR, Ian GRANT, Tim SMITH
  • CELL ISOLATION FOR USE IN AUTOMATED BIOREACTORS
    Publication number: 20200181562
    Abstract: The present disclosure provides cassettes for use in automated cell engineering systems that include cell separation filters for capturing a target cell population for automated processing. The disclosure also provides methods of separating a target cell population, as well as automated cell engineering systems using the cassettes and for carrying out the methods.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 11, 2020
    Inventors: Erika MCAFEE, Yaling SHI, Samatha BANDAPALLE, Eytan ABRAHAM
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20200071670
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: October 30, 2019
    Publication date: March 5, 2020
    Inventors: Yaling SHI, Erika MCAFEE, Samatha BANDAPALLE, Ann SIEHOFF, Timo GLEISSNER, Joseph O'CONNOR, Eytan ABRAHAM, Kelly PURPURA, Nuala TRAINOR, Timothy SMITH
  • END-TO-END CELL THERAPY AUTOMATION
    Publication number: 20190169572
    Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 6, 2019
    Inventors: Yaling SHI, Erika McAfee, Samatha Bandapalle, Ann Siehoff, Timo Gleissner, Joseph O'Connor, Eytan Abraham, Kelly Purpura, Nuala Trainor, Timothy Smith