Patents by Inventor Erika Secco

Erika Secco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial DNA sequence with optimized leader function in 5?(5?-UTR) for the over-expression of recombinant proteins in plants and method for the production of recombinant proteins in plants
    Patent number: 9976151
    Abstract: Artificial DNA of a 5?-UTR leader region, which artificial DNA is effective in increasing the expression of recombinant proteins in plants, and comprises, along the 5??3? direction, an Inr initiator site and a Kozak or Kozak-like consensus sequence, and also comprises, between the Inr initiator site and the Kozak or Kozak-like consensus sequence, a plurality of poly(CAA) and a plurality of poly(CT) regions, in the same number as the poly(CAA) regions wherein at least one, optionally each one, poly(CAA) region, in the 5??3? direction, is upstream of a poly(CT) region and at least one poly(CAA) region, in the 5??3? direction, is contiguous with a poly(CT) region, wherein the artificial DNA provides the absence of A/T-rich motifs, the absence of trinucleotide elements ATT, the absence of trinucleotide elements CTG and the absence of homopolymeric tracts, that is, sequences consisting of more than 3, optionally more than 4, identical nucleotides.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: May 22, 2018
    Assignee: ADIENNE Pharma & Biotech SA
    Inventors: Stefano Marchetti, Tamara Patti, Erika Secco
  • ARTIFICIAL DNA SEQUENCE WITH OPTIMIZED LEADER FUNCTION IN 5'(5'-UTR) FOR THE OVER-EXPRESSION OF RECOMBINANT PROTEINS IN PLANTS AND METHOD FOR THE PRODUCTION OF RECOMBINANT PROTEINS IN PLANTS
    Publication number: 20160130593
    Abstract: Artificial DNA of a 5?-UTR leader region, which artificial DNA is effective in increasing the expression of recombinant proteins in plants, and comprises, along the 5??3? direction, an Inr initiator site and a Kozak or Kozak-like consensus sequence, and also comprises, between the Inr initiator site and the Kozak or Kozak-like consensus sequence, a plurality of poly(CAA) and a plurality of poly(CT) regions, in the same number as the poly(CAA) regions wherein at least one, optionally each one, poly(CAA) region, in the 5??3? direction, is upstream of a poly(CT) region and at least one poly(CAA) region, in the 5??3? direction, is contiguous with a poly(CT) region, wherein the artificial DNA provides the absence of A/T-rich motifs, the absence of trinucleotide elements ATT, the absence of trinucleotide elements CTG and the absence of homopolymeric tracts, that is, sequences consisting of more than 3, optionally more than 4, identical nucleotides.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 12, 2016
    Applicant: RODING HOLDING S.A.
    Inventors: Stefano Marchetti, Tamara Patti, Erika Secco