Patents by Inventor Erika Von Euw

Erika Von Euw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLAUDIN-6 ANTIBODIES AND DRUG CONJUGATES
    Publication number: 20230049752
    Abstract: The present disclosure provides antigen-binding proteins which bind to Claudin-6 (CLDN6). In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: June 22, 2022
    Publication date: February 16, 2023
    Inventors: Dylan Conklin, Martina S. McDermott, Neil A. O'Brien, Michael J. Palazzolo, Dennis Slamon, Erika Von Euw, Peter Bowers
  • CLAUDIN6 ANTIBODIES AND METHODS OF TREATING CANCER
    Publication number: 20220372134
    Abstract: The present disclosure provides antigen-binding proteins which bind to Claudin-6 (CLDN6). In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: April 13, 2022
    Publication date: November 24, 2022
    Inventors: Dylan CONKLIN, Dennis Slamon, Neil A. O'Brien, Michael J. Palazzolo, Erika Von Euw
  • CLAUDIN-6 BISPECIFIC ANTIBODIES
    Publication number: 20220177583
    Abstract: The present disclosure provides bispecific antigen-binding proteins which bind to Claudin-6 (CLDN6) and a second antigen. In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 9, 2022
    Inventors: Dylan Conklin, Martina S. McDermott, Neil A. O'Brien, Michael J. Palazzolo, Dennis Slamon, Erika Von Euw, Peter Bowers
  • CLAUDIN-6 ANTIBODIES AND DRUG CONJUGATES
    Publication number: 20220162299
    Abstract: The present disclosure provides antigen-binding proteins which bind to Claudin-6 (CLDN6). In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: March 20, 2020
    Publication date: May 26, 2022
    Inventors: Dylan Conklin, Martina S. McDermott, Neil A. O'Brien, Michael J. Palazzolo, Dennis Slamon, Erika Von Euw, Peter Bowers
  • CLAUDIN6 ANTIBODIES AND METHODS OF TREATING CANCER
    Publication number: 20200291111
    Abstract: The present disclosure provides antigen-binding proteins which bind to Claudin-6 (CLDN6). In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: September 18, 2018
    Publication date: September 17, 2020
    Inventors: Dylan Conklin, Dennis Slamon, Neil A. O'Brien, Michael J. Palazzolo, Erika Von Euw
  • Biomarkers of Response to Cyclin D-CDK4/6 Targeted Therapies in Cancer
    Publication number: 20190292605
    Abstract: Provided herein are biomarkers indicating sensitivity or resistance to Cyclin D-CDK4/6 inhibitor therapy in cancer and methods of use.
    Type: Application
    Filed: March 29, 2019
    Publication date: September 26, 2019
    Inventors: Dennis Slamon, Richard Finn, Dylan Conklin, Erika von Euw
  • Biomarkers of Response to Cyclin D-CDK4/6 Targeted Therapies in Cancer
    Publication number: 20170067116
    Abstract: Provided herein are biomarkers indicating sensitivity or resistance to Cyclin D-CDK4/6 inhibitor therapy in cancer and methods of use.
    Type: Application
    Filed: March 4, 2015
    Publication date: March 9, 2017
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dennis Slamon, Richard Finn, Dylan Conklin, Erika Von Euw