Abstract: An adhesive skin patch including a substrate and an adhesive layer, wherein the substrate is formed of a foam sheet having breaking elongation of 100% or more, breaking strength of 20 N/20 mm or less, a density of 0.5 g/cm3 or less and a thickness of 0.300 mm or more, the adhesive layer is formed on one side of the substrate, and the adhesive layer contains an acrylic copolymer and a liquid or pasty component at room temperature.

Abstract: An adhesive skin patch including a substrate and an adhesive layer, wherein the substrate is formed of a foam sheet having open cells and a bubble fraction of 70% or more, and the adhesive layer is partially formed on one side of the substrate.

Abstract: A tape or sheet for sticking to skin, which includes a base material and an adhesive layer laminated on at least one surface of the base layer, wherein the adhesive layer contains an acrylic copolymer obtained by copolymerizing a monomer mixture including a (meth)acrylic acid alkyl ester monomer and an alkoxy group-containing ethylenically unsaturated monomer, a component that is liquid or paste-like at room temperature, and a tackifier, and wherein the tackifier includes a rosin ester.

Abstract: An adhesive preparation containing bisoprolol includes a backing and a pressure-sensitive adhesive layer formed on one side of the backing. The pressure-sensitive adhesive layer contains a polymer prepared through copolymerization of monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer (component (A)), a polymer prepared through copolymerization of monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer (component (B)), and bisoprolol (component (C)).

Abstract: An adhesive preparation containing bisoprolol includes a backing and a pressure-sensitive adhesive layer formed on one side of the backing. The pressure-sensitive adhesive layer contains a polymer prepared through copolymerization of monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer (component (A)), a polymer prepared through copolymerization of monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer (component (B)), and bisoprolol (component (C)).

Abstract: A patch preparation includes a support and a pressure-sensitive adhesive layer formed on one surface of the support. The pressure-sensitive adhesive layer includes: (A) a polymer prepared by copolymerizing monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer; (B) a polymer prepared by copolymerizing monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and (C) a basic drug, provided that bisoprolol and a salt thereof are excluded.

Abstract: A droplet formation device 1 includes: a base member 2 formed of stacked substrates including a middle substrate 21 and a lower substrate 23; a passage structure 211 formed on the middle substrate 21 and including droplet formation passages through which a liquid dispersed-phase material and a liquid continuous-phase material flow to form droplets of the dispersed-phase material using a shear force of the continuous-phase material; a liquid storage part 231 formed on the lower substrate 23 and storing the liquid dispersed-phase material 200 and the liquid of the continuous-phase material 100; dispersed-phase material supply parts through which the liquid dispersed-phase material 200 is supplied from the liquid storage part 231 to the droplet formation passages of the passage structure 211; and continuous-phase material supply parts through which the continuous-phase material 100 is supplied from the liquid storage part 231 to the droplet formation passages of the passage structure 211.

Abstract: The present invention relates to a gelatin particle, which is a thermally crosslinked non-porous spherical gelatin particle having a circularity of 0.8 or more and a dry particle diameter of 20 to 1,600 ?m. The average volume swelling ratio of the gelatin particle in a case where the gelatin particle is immersed in physiological saline at 23° C. is from 200 to 2,000% relative to an average volume of the gelatin particle in a dried state. As for a swollen gelatin particle, it is preferable that the gelatin used has a jelly strength of 80 to 120 g and the swollen gelatin particle has a particle diameter of 50 to 2,000 ?m. The gelatin particle can be used for blood vessel embolization and also for controlled release of physiologically active substance.