Patents by Inventor Eriko Ito

Eriko Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210122812
    Abstract: The present inventors discovered that incorporating an Fc region and an antigen-binding domain whose antigen-binding activity varies depending on ion concentration into an antigen-binding molecule that binds to an aggregate-forming antigen produces an antigen-binding molecule that can preferentially clear protein aggregates in comparison to protein monomers from plasma. Use of antigen-binding molecules of the present invention allows various diseases stemming from target tissues to be treated target-tissue-specifically. Use of antigen-binding molecules of the present invention enables treatment of diseases caused by protein aggregates.
    Type: Application
    Filed: January 8, 2021
    Publication date: April 29, 2021
    Inventors: Tomoyuki Igawa, Naoka Hironiwa, Eriko Ito
  • Publication number: 20210060254
    Abstract: A hollow medical needle is disclosed which includes: a hub part having an inner cavity connectable to a syringe; and a puncture part extending out toward an axial distal-end side of the hub part, by forming, at a distal end of the hub part, a puncture index part that includes a step perpendicular to an axial direction and is visible when abutting against a rubber stopper when the rubber stopper of a vial container is punctured by the puncture part, a position of an insertion terminal end substantially coincident with an outer surface of the rubber stopper is set at a fixed position when the puncture part is punctured into the rubber stopper.
    Type: Application
    Filed: November 11, 2020
    Publication date: March 4, 2021
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Minami MAEKAWA, Eriko ITO, Yoichiro IWASE, Toshiaki TAKAKI
  • Publication number: 20210040147
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: October 22, 2020
    Publication date: February 11, 2021
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20200207805
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20190352334
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: June 21, 2019
    Publication date: November 21, 2019
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20190062368
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: October 9, 2018
    Publication date: February 28, 2019
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20180162902
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: January 19, 2018
    Publication date: June 14, 2018
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20170275332
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 28, 2017
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20150353630
    Abstract: The present inventors discovered that incorporating an Fc region and an antigen-binding domain whose antigen-binding activity varies depending on ion concentration into an antigen-binding molecule that binds to an aggregate-forming antigen produces an antigen-binding molecule that can preferentially clear protein aggregates in comparison to protein monomers from plasma. Use of antigen-binding molecules of the present invention allows various diseases stemming from target tissues to be treated target-tissue-specifically. Use of antigen-binding molecules of the present invention enables treatment of diseases caused by protein aggregates.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 10, 2015
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tomoyuki Igawa, Naoka Hironiwa, Eriko Ito
  • Publication number: 20130018174
    Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.
    Type: Application
    Filed: December 24, 2010
    Publication date: January 17, 2013
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Igawa, Zenjiro Sampei, Tetsuya Wakabayashi, Eriko Ito
  • Publication number: 20100261401
    Abstract: The present invention relates to a toy figure around which textiles can be wrapped and attached comprising: at least one opening formed on a surface of said toy figure, an elastic member formed to cover each opening wherein a wavy incision is formed on each elastic member and the elastic member is exposed and visible from the opening.
    Type: Application
    Filed: June 18, 2010
    Publication date: October 14, 2010
    Inventors: Mariko Takano, Midori Itou, Saki Kawai, Yoshitaka Shido, Eriko Ito, Sayaka Kuroda, Danielle N. Armbrust, Penny Christine Towne-Vowles, Veronica Sandoval
  • Patent number: 7778625
    Abstract: An operation-mode control unit controls switching of an operation mode of a portable wireless terminal apparatus between a normal mode and an alarm mode. An alarm-data sending unit sends data pertaining to a situation of a user to a predetermined destination as alarm data, when the operation mode is switched to the alarm mode. In the normal mode, the portable wireless terminal apparatus performs normal functions, such as a phone call and an e-mail. In the alarm mode, the portable wireless terminal apparatus performs a user protecting function in addition to the normal functions, such as sending the alarm data to the predetermined destination.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: August 17, 2010
    Assignee: Fujitsu Limited
    Inventors: Osamu Yamauchi, Masahiro Harima, Atsushi Ito, Eriko Ito
  • Publication number: 20090083658
    Abstract: According to an aspect of an embodiment, a portable terminal having a display screen for displaying a plurality of emails on the display screen, the portable terminal includes: a receiving module for receiving a plurality of emails each having a body; a first display processing module for displaying the body of the email on the display screen; a detector for detecting the last of the body displayed on the display screen; and a second display processing module for displaying on the display screen a list of the plurality of the emails and status of each of the emails indicating whether the last of the body of each of the emails has been displayed.
    Type: Application
    Filed: September 18, 2008
    Publication date: March 26, 2009
    Applicant: FUJITSU LIMITED
    Inventors: Atsushi ITO, Iriichi OSANAI, Eriko ITO
  • Publication number: 20080183677
    Abstract: A mobile terminal controls an operation of an application such that the application which causes data recording records data related to the anniversary around a same time that the anniversary is notified. To be specific, the mobile terminal monitors whether a user has carried out an operation on the mobile terminal after the anniversary is notified. Upon the user carrying out an operation on the mobile terminal (any operation (for example, pressing a button of an operating unit etc.), the mobile terminal controls the operation by activating the application. The mobile terminal controls the operation by activating as the application, an imaging application that shoots and records an image, a memo input application that receives and records a memo input, and a mail application that transmits and records a mail.
    Type: Application
    Filed: November 29, 2007
    Publication date: July 31, 2008
    Applicant: FUJITSU LIMITED
    Inventors: Eriko ITO, Atsushi ITO, Naoto NISHIYAMA
  • Publication number: 20070026889
    Abstract: An operation-mode control unit controls switching of an operation mode of a portable wireless terminal apparatus between a normal mode and an alarm mode. An alarm-data sending unit sends data pertaining to a situation of a user to a predetermined destination as alarm data, when the operation mode is switched to the alarm mode. In the normal mode, the portable wireless terminal apparatus performs normal functions, such as a phone call and an e-mail. In the alarm mode, the portable wireless terminal apparatus performs a user protecting function in addition to the normal functions, such as sending the alarm data to the predetermined destination.
    Type: Application
    Filed: October 31, 2005
    Publication date: February 1, 2007
    Inventors: Osamu Yamauchi, Masahiro Harima, Atsushi Ito, Eriko Ito
  • Publication number: 20060211433
    Abstract: The present invention provides a portable electronic apparatus such as a portable telephone, which improves safety in a situation where the apparatus is left behind. The portable electronic apparatus includes: a storing section that stores a pair of designated time and designated position; a time obtaining section that obtains a current time; a position obtaining section that obtains a current position; a determination section that determines whether there is a match or a mismatch between the current position at the current time reaching the designated time and the designated position that is paired with the designated time; and a mismatch processing section that performs mismatch processing in response to a mismatch determined by the determination section as a determination result.
    Type: Application
    Filed: July 26, 2005
    Publication date: September 21, 2006
    Applicant: FUJITSU LIMITED
    Inventors: Eriko Ito, Atsushi Itoh, Masahiro Harima, Osamu Yamauchi, Hiroshi Fushikida, Tetsuya Murata, Hidenori Konno, Kousuke Taneda