Abstract: The present invention provides efficient methods based on alteration of the protein A-binding ability, for producing or purifying multispecific antibodies having the activity of binding to two or more types of antigens to high purity through a protein A-based purification step alone. The methods of the present invention for producing or purifying multispecific antibodies which feature altering amino acid residues of antibody heavy chain constant region and/or variable region. Multispecific antibodies with an altered protein A-binding ability, which exhibit plasma retention comparable or longer than that of human IgG1, can be efficiently prepared in high purity by introducing amino acid alterations of the present invention into antibodies.

Abstract: In a liquid crystal display device 100 provided by the present invention, at least a part of a circuit board 16 can be held on an outer side surface 30B of a frame 30 by a board clip 50 mounted on the outer side surface 30B of the frame 30. The board clip 50 includes a plate-like main body portion 52 located so as to face the outer side surface 30B of the frame 30, front-side engaging portions 54 and 55, and a pair of rear-side engaging portions 56 and 57. A bezel receiving portion 60 contactable with a part of a peripheral portion of a bezel 20 is formed in the vicinity of the front-side engaging portions 54 and 55.

Abstract: In a liquid crystal display device provided by the present invention, in a coupling part in which a plurality of frame components 32 and 42 forming a frame are coupled to each other, a part 53 of an end 50A of one of the frame components, i.e., the frame component 32, and a part 55 of an end 50B of the other frame component 42 overlap each other in a front-rear direction of the liquid crystal panel. Among the overlapping two ends 50A and 50B, the end facing an optical member 78 (member receiving portion 55) is close to the optical member 78, and is formed to be contactable with the optical member 78 in a surface-to-surface manner when the coupling part is bent toward the optical member 78.

Abstract: In a display device provided by the present invention, among a plurality of sides forming a frame 30, one pair of sides facing each other respectively have protrusions 52 and 62 and clearance adjusting members 54 and 64, for adjusting a clearance between the protrusions 52 and 62 and a display panel 10 located on an inner-side panel receiving portion, provided as at least partially extending toward the inner-side panel receiving portion. An extending portion, extending toward the inner-side panel receiving portion, of one of the clearance adjusting members, i.e., the clearance adjusting member 54, and an extending portion, extending toward the inner-side panel receiving portion, of the other clearance adjusting member 64, have different thicknesses from each other in respective extending directions thereof.

Abstract: In a liquid crystal display device 100 provided by the present invention, at least a part of a circuit board 16 can be held on an outer side surface 30B of a frame 30 by a board clip 50 mounted on the outer side surface 30B of the frame 30. The board clip 50 includes a plate-like main body portion 52 located so as to face the outer side surface 30B of the frame 30, front-side engaging portions 54 and 55, and a pair of rear-side engaging portions 56 and 57. A bezel receiving portion 60 contactable with a part of a peripheral portion of a bezel 20 is formed in the vicinity of the front-side engaging portions 54 and 55.