Abstract: An aqueous dentifrice formulation, comprising: a bioactive glass exhibiting at least one of: a hydrolytic resistance of glass grains (HGB) of at most 4, when measured by International Organization for Standardization section 719 (ISO 719); a weight loss of 5 wt. % or less after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; an XRD spectrum substantially free of crystalline phase after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; or any combination thereof; wherein, when the bioactive glass is contacted with artificial saliva, the bioactive glass forms a bioactive crystalline phase. A method of using the aqueous dentifrice formulation to remineralize enamel of the tooth, treat caries of the tooth, treat dentin hypersensitivity of the tooth, or any combination thereof.

Abstract: A silicate-based composition includes: 40-80 mol % SiO2, >0-25 mol % MO, 15-40 mol % R2O, >0-10 mol % Al2O3, >0-10 mol % P2O5, and >0-5 mol % ZrO2, such that MO is a sum of BeO, MgO, CaO, SrO, and BaO; and R2O is a sum of Li2O, Na2O, K2O, Rb2O, Cs2O.

Abstract: A glass-ceramic article includes a crystalline phase; a residual glass phase; greater than or equal to 52 mol % and less than or equal to 70 mol % SiO2, greater than or equal to 14 mol % and less than or equal to 35 mol % Li2O, greater than or equal to 0.1 mol % and less than or equal to 15 mol % CaO, greater than or equal to 0.5 mol % and less than or equal to 10 mol % ZrO2; and greater than or equal to 0.5 mol % and less than or equal to 5 mol % P2O5.

Abstract: A silicate-based glass composition includes 15-65 wt. % SiO2, 2.5-25 wt. % MgO, 1-30 wt. % P2O5, and 15-50 wt. % CaO. The glass composition may also include 0-5 wt. % F?, and 0-10 wt. % ZrO2. The glass composition may also include one of 0-10 wt. % Al2O3, 0-10 wt. % SrO, and 0-10 wt. % ZnO.

Abstract: A silicate-based glass composition includes: 40-60 wt. % SiO2, 0-10 wt. % B2O3, 0.01-10 wt. % P2O5, 0-10 wt. % Al2O3, 0-5 wt. % Li2O, 10-30 wt. % Na2O, 0.01-15 wt. % K2O, 0.01-5 wt. % MgO, 15-30 wt. % CaO, 15-35 wt. % MO, and 15-30 wt. % R2O, such that MO is the sum of MgO, CaO, SrO, BeO, and BaO, and R2O is the sum of Na2O, K2O, Li2O, Rb2O, and Cs2O.