Patents by Inventor Erin E. Murphy

Erin E. Murphy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and methods for deriving gene signature biomarkers of response to PD-1 antagonists
    Patent number: 11377693
    Abstract: A gene expression platform, which is a combination of a set of genes that are correlated with response to a PD-1 antagonist in multiple tumor types and a normalization gene set, is disclosed. A method and system of using the gene expression platform to derive gene signature biomarkers of anti-tumor response to a PD-1 antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: July 5, 2022
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Mark D. Ayers, Andrey Loboda, Jared K. Lunceford, Terrill K. McClanahan, Erin E. Murphy, Michael Nebozhyn
  • SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS
    Publication number: 20180327848
    Abstract: A gene expression platform, which is a combination of a set of genes that are correlated with response to a PD-1 antagonist in multiple tumor types and a normalization gene set, is disclosed. A method and system of using the gene expression platform to derive gene signature biomarkers of anti-tumor response to a PD-1 antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed.
    Type: Application
    Filed: December 8, 2015
    Publication date: November 15, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mark D. Ayers, Andrey Loboda, Jared K. Lunceford, Terrill K. McClanahan, Erin E. Murphy, Michael Nebozhyn
  • Nucleic acids encoding TNF?
    Patent number: 8426573
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: April 23, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20120164147
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: March 7, 2012
    Publication date: June 28, 2012
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Nucleic acid encoding TNFx protein
    Patent number: 8148507
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: April 3, 2012
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20110165165
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: December 21, 2010
    Publication date: July 7, 2011
    Applicant: Schering Corporation
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20100104576
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: December 22, 2009
    Publication date: April 29, 2010
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20090155242
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: September 22, 2008
    Publication date: June 18, 2009
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Mammalian genes; related reagents and methods
    Publication number: 20020142292
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: September 7, 2001
    Publication date: October 3, 2002
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Mammalian genes; related reagents
    Publication number: 20020143147
    Abstract: Purified genes from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding th polypeptides are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: April 23, 2001
    Publication date: October 3, 2002
    Inventors: Erin E. Murphy, Jeanine D. Mattson, Elizabeth Esther Mary Bates, Daniel M. Gorman, Serge J.E. Lebecque