Patents by Inventor Erin H. Christensen

Erin H. Christensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE
    Publication number: 20220064315
    Abstract: Provided herein are tetravalent antigen binding complexes having agonist activity for a cell surface receptor. In some embodiments, the complexes comprise binding specificities for multiple epitopes of the same cell surface receptor. Further provided herein are nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production related thereto.
    Type: Application
    Filed: May 17, 2021
    Publication date: March 3, 2022
    Applicant: Genentech, Inc.
    Inventors: Greg LAZAR, Yanli YANG, Erin H. CHRISTENSEN, Julie HANG, Jeong KIM, Seth HARRIS
  • Multivalent and multiepitopic antibodies having agonistic activity and methods of use
    Patent number: 11046776
    Abstract: Provided herein are tetravalent antigen binding complexes having agonist activity for a cell surface receptor. In some embodiments, the complexes comprise binding specificities for multiple epitopes of the same cell surface receptor. Further provided herein are nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production related thereto.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: June 29, 2021
    Assignee: Genentech, Inc.
    Inventors: Greg Lazar, Yanli Yang, Erin H. Christensen, Julie Hang, Jeong Kim, Seth Harris
  • Coiled coil and/or tether containing protein complexes and uses thereof
    Patent number: 9994646
    Abstract: The invention provides engineered protein complexes constructed using a coiled coil and/or a tether and methods for making, using, and purifying such complexes, such as multispecific antibodies or other multispecific Fc containing complexes.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: June 12, 2018
    Assignee: Genentech, Inc.
    Inventors: Erin H. Christensen, Dan L. Eaton, Andrew C. Vendel, Bernd Wranik
  • MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE
    Publication number: 20180057598
    Abstract: Provided herein are tetravalent antigen binding complexes having agonist activity for a cell surface receptor. In some embodiments, the complexes comprise binding specificities for multiple epitopes of the same cell surface receptor. Further provided herein are nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production related thereto.
    Type: Application
    Filed: August 4, 2017
    Publication date: March 1, 2018
    Applicant: Genentech, Inc.
    Inventors: Greg LAZAR, Yanli YANG, Erin H. CHRISTENSEN, Julie HANG, Jeong KIM, Seth HARRIS
  • Single-chain antibodies and other heteromultimers
    Patent number: 9688758
    Abstract: The invention provides engineered heteromultimeric protein complexes constructed using one, two, or three tethers and methods for making, using, and purifying such complexes, such as antibodies with different binding properties.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: June 27, 2017
    Assignee: GENENTECH, INC.
    Inventors: Bernd Wranik, Dan L. Eaton, Erin H. Christensen, Jiansheng Wu
  • COILED COIL AND/OR TETHER CONTAINING PROTEIN COMPLEXES AND USES THEREOF
    Publication number: 20160002356
    Abstract: The invention provides engineered protein complexes constructed using a coiled coil and/or a tether and methods for making, using, and purifying such complexes, such as multispecific antibodies or other multispecific Fc containing complexes.
    Type: Application
    Filed: June 9, 2015
    Publication date: January 7, 2016
    Inventors: Erin H. CHRISTENSEN, Dan L. EATON, Andrew C. VENDEL, Bernd WRANIK
  • SINGLE-CHAIN ANTIBODIES AND OTHER HETEROMULTIMERS
    Publication number: 20150133638
    Abstract: The invention provides engineered heteromultimeric protein complexes constructed using one, two, or three tethers and methods for making, using, and purifying such complexes, such as antibodies with different binding properties.
    Type: Application
    Filed: August 8, 2014
    Publication date: May 14, 2015
    Applicant: GENENTECH, INC.
    Inventors: BERND WRANIK, DAN L. EATON, ERIN H. CHRISTENSEN, JIANSHENG WU
  • COILED COIL AND/OR TETHER CONTAINING PROTEIN COMPLEXES AND USES THEREOF
    Publication number: 20120302737
    Abstract: The invention provides engineered protein complexes constructed using a coiled coil and/or a tether and methods for making, using, and purifying such complexes, such as multispecific antibodies or other multispecific Fc containing complexes.
    Type: Application
    Filed: September 16, 2010
    Publication date: November 29, 2012
    Applicant: Genentech, Inc.
    Inventors: Erin H. Christensen, Dan L. Eaton, Andrew C. Vendel, Bernd Wranik