Abstract: A bedding article for a domestic animal comprising an outer textile casing defining a geometric shape for supporting a domestic animal, an inner filling, and a microbe-inhibiting agent or property applied to at least one of the outer textile casing and the inner filling. The bedding article may be fabricated in various shapes, designs, and styles; e.g., rectangular, circular, elliptical, with or without upstanding side walls, etc. A process for applying the microbe-inhibiting agent or property to at least one on the outer textile casing and the inner filling is provided. Application methods include spraying, dipping, brushing, and rolling the microbe-inhibiting agent or property onto at least one of the outer textile casing and the inner filling.