Patents by Inventor Erin M. Baker
Erin M. Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9966244Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: October 23, 2017Date of Patent: May 8, 2018Assignee: Battelle Memorial InstituteInventors: Gordon A. Anderson, Erin M. Baker, Richard D. Smith, Yehia M. Ibrahim
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Publication number: 20180061621Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: ApplicationFiled: October 23, 2017Publication date: March 1, 2018Inventors: Gordon A. Anderson, Erin M. Baker, Richard D. Smith, Yehia M. Ibrahim
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Publication number: 20170345634Abstract: A system and method for providing sample into an electrospray device such as a mass spectrometer by providing a sample at a near constant flow through a sample delivery tube with a specified dimensionality through an emitter. These dimensions and feed rates result in higher pressures than would exist in the prior art with some of these pressures being greater than 1000 psi. This system enables increased sample throughput of up to 1200 samples per day.Type: ApplicationFiled: May 15, 2017Publication date: November 30, 2017Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Daniel J. Orton, Ronald J. Moore, Erin M. Baker
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Patent number: 9812311Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: January 13, 2014Date of Patent: November 7, 2017Assignee: Battelle Memorial InstituteInventors: Gordon A. Anderson, Erin M. Baker, Richard D. Smith, Yehia M. Ibrahim
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Patent number: 9651563Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.Type: GrantFiled: July 14, 2015Date of Patent: May 16, 2017Assignee: Battelle Memorial InstituteInventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton
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Publication number: 20160071715Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: ApplicationFiled: January 13, 2014Publication date: March 10, 2016Inventors: Gordon A. Anderson, Erin M. Baker, Richard D. Smith, Yehia M. Ibrahim
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Publication number: 20150323551Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.Type: ApplicationFiled: July 14, 2015Publication date: November 12, 2015Applicant: Battelle Memorial InstituteInventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton
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Patent number: 9134326Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.Type: GrantFiled: March 13, 2014Date of Patent: September 15, 2015Assignee: Battelle Memorial InstituteInventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton
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Publication number: 20150076343Abstract: An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.Type: ApplicationFiled: October 30, 2014Publication date: March 19, 2015Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Aleksey Tolmachev, Richard D. Smith, Yehia M. Ibrahim, Gordon A. Anderson, Erin M. Baker
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Patent number: 8969800Abstract: An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.Type: GrantFiled: October 30, 2014Date of Patent: March 3, 2015Assignee: Battelle Memorial InstituteInventors: Aleksey Tolmachev, Richard D. Smith, Yehia M. Ibrahim, Gordon A. Anderson, Erin M. Baker
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Patent number: 8907273Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: May 30, 2014Date of Patent: December 9, 2014Assignee: Battelle Memorial InstituteInventors: Tsung-Chi Chen, Keqi Tang, Yehia M. Ibrahim, Richard D. Smith, Gordon A. Anderson, Erin M. Baker
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Patent number: 8901490Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: May 30, 2014Date of Patent: December 2, 2014Assignee: Battelle Memorial InstituteInventors: Tsung-Chi Chen, Keqi Tang, Yehia M. Ibrahim, Richard D. Smith, Gordon A. Anderson, Erin M. Baker
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Publication number: 20140299766Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: ApplicationFiled: January 3, 2014Publication date: October 9, 2014Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Gordon A. Anderson, Richard D. Smith, Yehia M. Ibrahim, Erin M. Baker
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Publication number: 20140273275Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: BATTELLE MEMORIAL INSTITUTEInventors: JON M. JACOBS, KRISTIN E. BURNUM-JOHNSON, ERIN M. BAKER, RICHARD D. SMITH, MARINA A. GRITSENKO, DANNY ORTON
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Patent number: 8835839Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: January 3, 2014Date of Patent: September 16, 2014Assignee: Battelle Memorial InstituteInventors: Gordon A. Anderson, Richard D. Smith, Yehia M. Ibrahim, Erin M. Baker