Abstract: A method for calibration of vision sensors includes, by a processor: selecting a calibration sequence that has a base calibration pattern and calibration angles, generating a calibrating target that may include the calibration pattern at a selected calibration angle of the angles, and causing a display screen to display a digital image representative of the target at the selected angle relative to an originating border of the selected angle. Each of the calibration angles is associated with a different originating border of the screen. The method includes by a vision sensor capturing at least one image of the calibrating target displayed on the screen. The calibration is repeated for each calibration angle of the sequence. The method includes performing calibration of the vision sensor in response to image signal processing of extracted calibration features in the at least one image of the calibrating targets.