Abstract: Various embodiments respond to a query in a cognitive decision-making system. In one embodiment, a query is received and a plurality of analytical tools defined in a knowledge base that are to be used to produce a response are identified. A workflow sequence is constructed based on a dependency graph of the identified analytical tools. Each analytical tool within the workflow sequence is executed to create a plurality of outputs. The workflow sequence is updated based on the outputs and the response is provided based on the outputs. At least one of a topic, an entity, a relationship and an unknown parameter within the query may be identified using natural language processing. The analytical tools may be digital tools or physical tools. Feedback on the response is received based on a confidence level and the knowledge base is updated based on the received feedback.