Abstract: Improved systems and methods for medicine delivery, and in particular, improved insulin pen needles and related devices are provided. Smart injection devices record and transfer data including medicine level, delivered dose, dose confirmation, and dose time and date. Additional data captured may include glucose concentration, insulin level, carbohydrates ingested, stress level, exercise, blood pressure, and glucose high and low excursion events. Various means of data collection and analysis are provided and systems can identify and flag patients who require intervention. Smart sleeves and add sensing capability to standard insulin pens. Pen needles are provided with sensing capability to confirm and measure doses delivered by insulin pen. A two-part pen cap include a primary sleeve that connects to the insulin pen and an end cap that provides for capturing the time of dose delivery, and monitoring the hold time for a dose delivery after plunger movement.

Abstract: Improved systems and methods for medicine delivery, and in particular, improved insulin pen needles and related devices are provided. Smart injection devices record and transfer data including medicine level, delivered dose, dose confirmation, and dose time and date. Additional data captured may include glucose concentration, insulin level, carbohydrates ingested, stress level, exercise, blood pressure, and glucose high and low excursion events. Various means of data collection and analysis are provided and systems can identify and flag patients who require intervention. Smart sleeves and add sensing capability to standard insulin pens. Pen needles are provided with sensing capability to confirm and measure doses delivered by insulin pen. A two-part pen cap include a primary sleeve that connects to the insulin pen and an end cap that provides for capturing the time of dose delivery, and monitoring the hold time for a dose delivery after plunger movement.

Abstract: A cartridge is configured to be inserted into a medical instrument for treating patients with radioactive seeds. The cartridge includes a rotating internal barrel that is loaded with a plurality of seeds, where the internal barrel has a plurality of conduits for accepting the seeds. As the internal barrel rotates, a seed from one of the conduits is deposited into a shuttle, and then the shuttle is fully extended so as to provide the seed to the medical instrument. The shuttle is then retracted, and the barrel is rotated to the next conduit, so as to receive a seed from that next conduit. The cartridge includes a first shield and a second shield, each having slots where the slots of the first and second shields are aligned in a first verification or calibration mode, and where the slots are not aligned in a normal, seed depositing mode. The second shield also includes a plurality of numeric indicators that indicate a current number of seeds remaining in the cartridge.

Abstract: A medical instrument provides for precise indexing in order to implant seeds into seed implant locations within a patient. The medical instrument is affixed to a targeting fixture, and upon operator actuation of a trigger, is automatically indexed from one seed implant location to a next seed implant location.

Abstract: A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal and to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore to eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.

Abstract: A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.

Abstract: A method for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.

Abstract: A method for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.

Abstract: A cartridge is configured to be inserted into a medical instrument for treating patients with radioactive seeds. The cartridge includes a rotating internal barrel that is loaded with a plurality of seeds, where the internal barrel has a plurality of conduits for accepting the seeds. As the internal barrel rotates, a seed from one of the conduits is deposited into a shuttle, and then the shuttle is fully extended so as to provide the seed to the medical instrument. The shuttle is then retracted, and the barrel is rotated to the next conduit, so as to receive a seed from that next conduit. The cartridge includes a first shield and a second shield, each having slots where the slots of the first and second shields are aligned in a first verification or calibration mode, and where the slots are not aligned in a normal, seed depositing mode. The second shield also includes a plurality of numeric indicators that indicate a current number of seeds remaining in the cartridge.

Abstract: A medical instrument provides for precise indexing in order to implant seeds into seed implant locations within a patient. The medical instrument is affixed to a targeting fixture, and upon operator actuation of a trigger, is automatically indexed from one seed implant location to a next seed implant location.

Abstract: A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore to eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.