Patents by Inventor Ernest Allen Sickmier

Ernest Allen Sickmier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STAT MODULATORS AND USES THEREOF
    Publication number: 20250215030
    Abstract: Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with STAT3 and/or STAT6.
    Type: Application
    Filed: March 30, 2023
    Publication date: July 3, 2025
    Inventors: Neil Bifulco, Howard Bregman, Giovanni Cianchetta, Brian Hodous, Samuel K. Reznik, Yong Tang, Andrew Tasker, Rishi G. Vaswani, Ernest Allen Sickmier, John Yeoman, Xia Tian
  • STAT MODULATORS AND USES THEREOF
    Publication number: 20250215029
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with STAT3 and/or STAT6.
    Type: Application
    Filed: January 10, 2023
    Publication date: July 3, 2025
    Inventors: Howard Bregman, Neil Bifulco, Giovanni Cianchetta, Brian Hodous, Samuel K. Reznik, Ernest Allen Sickmier, Yong Tang, Andrew Tasker, Xia Tian, Rishi G. Vaswani, John Yeoman
  • 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS
    Publication number: 20250179103
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with STAT3 and/or STAT6, such as e.g. cancer and inflammatory conditions. Preferred compounds are 6-oxodecahydropyrrolo[1,2-a][1,5]diazocine and 6-oxodecahydro-4H-pyrrolo[2,1-d][1,5]thiazocine derivatives.
    Type: Application
    Filed: February 27, 2023
    Publication date: June 5, 2025
    Inventors: Neil Bifulco, Howard Bregman, Giovanni Cianchetta, Brian Hodous, Samuel K. Reznik, Yong Tang, Andrew Tasker, Rishi G. Vaswani, Ernest Allen Sickmier, John Yeoman, Xia Tian
  • INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF
    Publication number: 20250179013
    Abstract: Provided are compounds of the Formula (I): or pharmaceutically acceptable salts thereof, which are useful for the inhibition of DHX9 and in the treatment of a variety of DHX9 mediated conditions or diseases, such as cancer.
    Type: Application
    Filed: February 17, 2023
    Publication date: June 5, 2025
    Inventors: Matthew H. Daniels, Kenneth W. Duncan, Brian Andrew Sparling, Young-tae Lee, Jennifer Castro, Scott Ribich, Ernest Allen Sickmier, Andrew Stewart Tasker, James Edward John Mills
  • INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF
    Publication number: 20250145597
    Abstract: Provided are compounds of the Formula (I): or pharmaceutically acceptable salts thereof, which are useful for the inhibition of DHX9 and in the treatment of a variety of DHX9 mediated conditions or diseases, such as cancer.
    Type: Application
    Filed: October 23, 2024
    Publication date: May 8, 2025
    Inventors: Matthew H. Daniels, Kenneth W. Duncan, Brian Andrew Sparling, Young-tae Lee, Jennifer Castro, Scott Ribich, Ernest Allen Sickmier, Andrew Stewart Tasker, James Edward John Mills, Gavin Whitlock, Andrew J. Jennings
  • METTL3 MODULATORS
    Publication number: 20240051985
    Abstract: Provided are compounds of Formula (I?) or (I) below, or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: October 13, 2021
    Publication date: February 15, 2024
    Inventors: Matthew H. Daniels, Thomas Andrew Wynn, Brian Andrew Sparling, Ernest Allen Sickmier, Andrew Stewart Tasker, James Edward John Mills
  • METTL3 MODULATORS
    Publication number: 20230027361
    Abstract: Provided are compounds of Formula (I?) or (II?), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: October 20, 2020
    Publication date: January 26, 2023
    Applicant: Accent Therapeutics, Inc.
    Inventors: Thomas Andrew Wynn, Brian Lewis Hodous, Paula Ann Boriack-Sjodin, Ernest Allen Sickmier, James Edward John Mills, Robert A. Copeland, Andrew Stewart Tasker, Matthew H. Daniels, Kenneth W. Duncan, Brian Andrew Sparling
  • METTL3 MODULATORS
    Publication number: 20220372040
    Abstract: Provided are compounds of Formula (I?) or (I) below, or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: October 22, 2020
    Publication date: November 24, 2022
    Applicants: Accent Therapeutics, Inc., Accent Therapeutics, Inc.
    Inventors: Thomas Andrew Wynn, Brian Lewis Hodous, Paula Ann Boriack-Sjodin, Ernest Allen Sickmier, James Edward John Mills, Andrew Stewart Tasker, Robert A. Copeland