Patents by Inventor Ernest J. Mueller

Ernest J. Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using stabilized compositions of thermostable DNA polymerase and anionic detergent
    Patent number: 8404464
    Abstract: The present invention provides compositions, methods, and kits for protecting thermostable DNA polymerase during amplification reactions conducted at a temperature ranging from about 40° C. to greater than 100° C. The composition comprises a thermostable DNA polymerase and an anionic detergent or zwitterionic detergent.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: March 26, 2013
    Assignee: Sigma-Aldrich Co., LLC
    Inventors: Brian W. Ward, Ernest J. Mueller, Jessica Copeland, Deborah Vassar
  • STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT
    Publication number: 20110312035
    Abstract: The present invention provides compositions, methods, and kits for protecting thermostable DNA polymerase during amplification reactions conducted at a temperature ranging from about 40° C. to greater than 100° C. The composition comprises a thermostable DNA polymerase and an anionic detergent or zwitterionic detergent.
    Type: Application
    Filed: April 22, 2011
    Publication date: December 22, 2011
    Applicant: SIGMA-ALDRICH CO.
    Inventors: Brian W. Ward, Ernest J. Mueller, Jessica Copeland, Deborah Vassar
  • Stabilized compositions of thermostable DNA polymerase and anionic or zwitterionic detergent
    Patent number: 7972828
    Abstract: The present invention provides compositions, methods, and kits for protecting thermostable DNA polymerase during amplification reactions conducted at a temperature ranging from about 40° C. to greater than 100° C. The composition comprises a thermostable DNA polymerase and an anionic detergent or zwitterionic detergent.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: July 5, 2011
    Assignee: Sigma-Aldrich Co.
    Inventors: Brian W. Ward, Ernest J. Mueller, Jessica Copeland, Deborah Vassar
  • Methods and Compositions for Amplification of DNA
    Publication number: 20090263871
    Abstract: The invention provides an Enzyme Blend comprising a DNA polymerase and a DNA repair enzyme. Methods and kits for amplification of DNA that is damaged, undamaged, or suspected of being damaged are also provided.
    Type: Application
    Filed: June 23, 2009
    Publication date: October 22, 2009
    Applicant: SIGMA-ALDRICH CO.
    Inventors: Christopher L. Walker, Ernest J. Mueller, Kevin J. Kayser, Jason S. Milligan, Erik R. Eastlund
  • STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT
    Publication number: 20080145910
    Abstract: The present invention provides compositions, methods, and kits for protecting thermostable DNA polymerase during amplification reactions conducted at a temperature ranging from about 40° C. to greater than 100° C. The composition comprises a thermostable DNA polymerase and an anionic detergent or zwitterionic detergent.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 19, 2008
    Applicant: SIGMA ALDRICH COMPANY
    Inventors: Brian W. Ward, Ernest J. Mueller, Jessica Copeland, Deborah Vassar
  • Methods and Compositions for Amplification of DNA
    Publication number: 20080124768
    Abstract: Compositions for the amplification of damaged nucleic acids are disclosed. The compositions generally comprise a mesophilc polymerase, a thermostable polymerase, and an AP endonuclease. Methods of using the same for the amplification of damaged DNA are also disclosed.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 29, 2008
    Applicant: Sigma Aldrich Co.
    Inventors: Ernest J. Mueller, Kevin J. Kayser, Brian W. Ward, Christopher Walker, Erik Eastlund, Jason Milligan