Patents by Inventor Ernest John Alexander

Ernest John Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 9-Benzoyl,3-hydroxymethyl-1,2,3,4-tetrahydro-carbazole
    Patent number: 4028382
    Abstract: 9-Benzoyl-3-hydroxymethyl-1,2,3,4-tetrahydrocarbazole and 9-benzoyl-3-(N-phenylcarbamoyloxymethyl)-1,2,3,4-tetrahydrocarbazole, having respectively antiinflammatory and antibacterial activities, and their preparation are described.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: June 7, 1977
    Assignee: Sterling Drug Inc.
    Inventors: Ernest John Alexander, Aram Mooradian
  • 9-Benzoyl-1,2,3,4-tetrahydrocarbazole
    Patent number: 4001270
    Abstract: 9-Benzoyl-3-hydroxymethyl-1,2,3,4-tetrahydrocarbazole and 9-benzoyl-3-(N-phenylcarbamoyloxymethyl)-1,2,3,4-tetrahydrocarbazole, having respectively antiinflammatory and antibacterial activities, and their preparation are described.
    Type: Grant
    Filed: December 12, 1975
    Date of Patent: January 4, 1977
    Assignee: Sterling Drug Inc.
    Inventors: Ernest John Alexander, Aram Mooradian
  • 1,2,3,4-Tetrahydrocarbazoles
    Patent number: 3979391
    Abstract: Novel 4-R.sub.1 R.sub.2 NCH.sub.2 -9-benzyl-6-R.sub.3 -7-R.sub.4 -1,2,3,4-tetrahydrocarbazoles having antibacterial activity are disclosed. The compounds are prepared by the chemical reduction of the corresponding 4-R.sub.1 R.sub.2 NCO-9-benzyl-6-R.sub.3 -7-R.sub.4 -1,2,3,4-tetrahydrocarbazoles.
    Type: Grant
    Filed: August 4, 1975
    Date of Patent: September 7, 1976
    Assignee: Sterling Drug Inc.
    Inventors: Ernest John Alexander, Aram Mooradian
  • 2-(Piperazinoethyl)-6,7-dihydroindol)[1,7-an] [1]benzazepine
    Patent number: 3963721
    Abstract: Novel 2-(aminoalky)-6,7-dihydroindolo[1,7-ab] 1,7-ab][1]benzazepines and acid-addition salts thereof having antibacterial activity, and intermediate and process for the preparation thereof are disclosed.
    Type: Grant
    Filed: June 19, 1975
    Date of Patent: June 15, 1976
    Assignee: Sterling Drug Inc.
    Inventor: Ernest John Alexander
  • 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids
    Patent number: 3948939
    Abstract: Novel 9-aroyl-1,2,3,4-tetrahydrocarbazoles bearing a carboxy substituent at position 3 or 4 and corresponding esters having antiinflammatory activity, the preparation thereof and novel intermediates therefor are described.
    Type: Grant
    Filed: October 15, 1974
    Date of Patent: April 6, 1976
    Assignee: Sterling Drug Inc.
    Inventors: Ernest John Alexander, Aram Mooradian
  • 3-Halomethylcarbonyl-9-benzoyl-1,2,3,4-tetrahydrocarbazoles
    Patent number: 3941805
    Abstract: Novel 3-Z-9-benzoyl-1,2,3,4-tetrahydrocarbazoles, wherein Z is CONR.sub.5 R.sub.6, CONHOH, CN, or COCH.sub.2 X, where X is chloro or bromo, having antimicrobial and/or anti-inflammatory activity are disclosed. Compounds wherein Z is CONR.sub.5 R.sub.6 and CONHOH are prepared from the corresponding 3-carboxylic acids by conversion to the corresponding acid chlorides and subsequent reaction with the appropriate amines and hydroxylamine respectively; compounds where Z is CN are prepared by the dehydration of the corresponding compounds where Z is CONH.sub.2 ; and the compounds where Z is COCH.sub.2 X are prepared by reacting hydrogen chloride or bromide with the corresponding compounds where Z is COCHN.sub.2 which in turn is prepared from the corresponding 3-carboxylic acid chloride by reaction with diazomethane.
    Type: Grant
    Filed: February 20, 1974
    Date of Patent: March 2, 1976
    Assignee: Sterling Drug Inc.
    Inventor: Ernest John Alexander
  • 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
    Patent number: 3939177
    Abstract: Novel 4-R.sub.1 R.sub.2 NCH.sub.2 -9-benzyl-6-R.sub.3 -7-R.sub.4 -1,2,3,4-tetrahydrocarbazoles having antibacterial activity are disclosed. The compounds are prepared by the chemical reduction of the corresponding 4-R.sub.1 R.sub.2 NCO-9-benzyl-6-R.sub.3 -7-R.sub.4 -1,2,3,4-tetrahydrocarbazoles.
    Type: Grant
    Filed: November 22, 1972
    Date of Patent: February 17, 1976
    Assignee: Sterling Drug Inc.
    Inventors: Ernest John Alexander, Aram Mooradian