Patents by Inventor Ernest M Coffey

Ernest M Coffey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for making populations of defined nucleic acid molecules
    Patent number: 8753811
    Abstract: The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: June 17, 2014
    Assignee: Cold Spring Harbor Laboratory
    Inventors: Stephen H. Friend, Michele A. Cleary, Ernest M. Coffey, Kristopher A. Killian, Gregory J. Hannon, Patrick Paddison
  • METHOD FOR MAKING POPULATIONS OF DEFINED NUCLEIC ACID MOLECULES
    Publication number: 20120149602
    Abstract: The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules.
    Type: Application
    Filed: February 16, 2012
    Publication date: June 14, 2012
    Inventors: Stephen H. FRIEND, Michele A. CLEARY, Kristopher A. KILIAN, Ernest M. COFFEY, Gregory J. HANNON, Patrick PADDISON
  • Method for making populations of defined nucleic acid molecules
    Patent number: 8133670
    Abstract: The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: March 13, 2012
    Assignees: Cold Spring Harbor Laboratory, Merck & Co., Inc.
    Inventors: Stephen H Friend, Michele A Cleary, Kristopher A Kilian, Ernest M Coffey, Gregory J Hannon, Patrick Paddison
  • Method for making populations of defined nucleic acid molecules
    Publication number: 20040259146
    Abstract: The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules.
    Type: Application
    Filed: June 2, 2004
    Publication date: December 23, 2004
    Applicants: Rosetta Inpharmatics LLC, Cold Spring Harbor Laboratory
    Inventors: Stephen H. Friend, Michele A. Cleary, Kristopher A. Kilian, Ernest M. Coffey, Gregory J. Hannon