Patents by Inventor Ernest Magnien

Ernest Magnien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinolinyl ether or thioether tetrazoles as agents for the treatment of hypersensitive ailments
    Patent number: 4874769
    Abstract: This invention relates to certain quinolyl ether and thioether tetrazoles and their use as valuable pharmaceutical agents for the treatment of hypersensitive ailments, particularly as lipoxygenase inhibitors and/or leukotriene antagonists possessing anti-inflammatory and antiallergic properties.
    Type: Grant
    Filed: January 5, 1988
    Date of Patent: October 17, 1989
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: Raymond Youssefyeh, Utpal Chakraborty, Ernest Magnien, Rohit Desai, Thomas D-Y Lee
  • Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
    Patent number: 4839369
    Abstract: Aryl and Heteroaryl Ethers are used for their anti-inflammatory and anti-allergic properties.
    Type: Grant
    Filed: March 13, 1986
    Date of Patent: June 13, 1989
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: Raymond Youssefyeh, Utpal Chakraborty, Ernest Magnien, Rohit Desai
  • Bisbenzothiazine, bisbenzodiazine and bisquinoline pharmaceutical compositions and use
    Patent number: 4666909
    Abstract: Compounds of the formula: ##STR1## wherein, R is H, alkyl, cycloalkyl, aryl or heteroaryl;R.sub.1 is H, alkyl, cycloalkyl, aryl, heteroaryl, substituted heteroaryl, aralkyl, substituted aryl, halo, OR.sup.2, SR.sup.2, NR.sub.2, CF.sub.3, NO.sub.2, CN, COOR.sup.2, CHO, SO.sub.3 H or SO.sub.2 NH.sub.2,whereinR.sup.2 is H, methyl, ethyl or propyl;Y is ##STR2## Z is O, S, NH or CH.sub.2 ; X is ##STR3## wherein R.sup.2 is H, methyl, ethyl or propyl;n is 1-10, and pharmaceutically acceptable salts thereof have antiallergy and antiinflammatory activity.
    Type: Grant
    Filed: September 16, 1985
    Date of Patent: May 19, 1987
    Assignee: USV Pharmaceutical Corp.
    Inventors: Howard Jones, Ernest Magnien, John H. Musser, Mujahid L. Shaikh
  • Bisbenzoxazines and pharmaceutical use
    Patent number: 4552876
    Abstract: Compounds of the formula: ##STR1## wherein, R is H, alkyl, cycloalkyl, aryl, or heteroaryl;R.sub.1 is H, alkyl, cycloalkyl, aryl, heteroaryl, substituted heteroaryl, aralkyl, substituted aryl, halo, OR.sup.2, SR.sup.2, NR.sub.2, CF.sub.3, NO.sub.2, CN, COOR.sup.2, CHO, SO.sub.3 H or SO.sub.2 NH.sub.2,whereinR.sup.2 is H, methyl, ethyl or propyl;Y is ##STR2## Z is O, S, NH or CH.sub.2 ; X is --CH.sub.2 --, ##STR3## or --(CH.sub.2).sub.n CHOH(CH.sub.2).sub.n --; whereinR.sup.2 is H, methyl, ethyl or propyl;n is 1-10, and pharmaceutically acceptable salts thereof have antiallergy and antiinflammatory activity.
    Type: Grant
    Filed: July 9, 1984
    Date of Patent: November 12, 1985
    Assignee: USV Pharmaceutical Corp.
    Inventors: Howard Jones, Ernest Magnien, John H. Musser, Mujahid L. Shaikh
  • Piperazines 1-hexyl-4(3-ketohexyl)
    Patent number: 4523014
    Abstract: Substituted piperazines of the following formula ##STR1## wherein R.sub.1 is C.sub.3 -C.sub.7 alkyl; R.sub.2 is keto or hydroxy C.sub.3 -C.sub.7 alkyl, keto C.sub.4 -C.sub.8 cycloakyl, C.sub.4 -C.sub.8 cycloalkyl keto C.sub.3 -C.sub.7 alkyl and pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: January 17, 1983
    Date of Patent: June 11, 1985
    Assignee: USV Pharmaceutical Corporation
    Inventors: Bernard Loev, Ernest Magnien