Patents by Inventor Ernest S. Y. Wong

Ernest S. Y. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZED PICOPLATIN ORAL DOSAGE FORM
    Publication number: 20150196494
    Abstract: The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox-active, metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt % picoplatin wherein the picoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt % of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt % of a lubricant. The dosage form can further include a dispersant.
    Type: Application
    Filed: March 25, 2015
    Publication date: July 16, 2015
    Inventors: Alistair J. Leigh, Christopher A. Procyshyn, Ernest S.Y. Wong, Christen M. Giandomenico
  • STABILIZED PICOPLATIN ORAL DOSAGE FORM
    Publication number: 20130183433
    Abstract: The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox- active metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt % picoplatin wherein the pieoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt % of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt % of a lubricant. The dosage form can further include a dispersant.
    Type: Application
    Filed: August 16, 2012
    Publication date: July 18, 2013
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Alistair J. Leigh, Christopher A. Procyshyn, Ernest S.Y. Wong, Christen M. Giandomenico
  • STABILIZED PICOPLATIN ORAL DOSAGE FORM
    Publication number: 20110033528
    Abstract: The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox-active metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt % picoplatin wherein the picoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt % of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt % of a lubricant. The dosage form can further include a dispersant.
    Type: Application
    Filed: August 5, 2009
    Publication date: February 10, 2011
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Alistair J. Leigh, Christopher A. Procyshyn, Ernest S.Y. Wong, Christen M. Giandomenico
  • Platinum complexes as antitumor agents
    Patent number: 6894049
    Abstract: The present invention relates to platinum antitumor drugs. In particular, it relates to platinum complexes having formula Ia or Ib or a pharmaceutically acceptable salt thereof wherein: each A is independently an anion; each B is independently halo, hydroxy, carboxylate, carbamate or a carbonate ester, Z is a substituted 5- or 6-membered, heterocyclic moiety wherein at least one substituent sterically hinders access of the Pt atom to a DNA strand of a tumor cell, and wherein Z is other than pyridine; and X is NH3 or mono- or dialkyl substituted NH3. which are active against cancer cells and have improved aqueous solubility and activity.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: May 17, 2005
    Assignee: AnorMED, Inc.
    Inventors: Ernest S. Y. Wong, Christen M. Giandomenico
  • Process for preparing amine platinum complexes
    Patent number: 6518428
    Abstract: The present invention relates to the area of platinum drugs.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: February 11, 2003
    Assignee: Anormed, Inc.
    Inventors: Ernest S. Y. Wong, Christen M. Gianomenico
  • Pt(IV) antitumor agent
    Patent number: 6413953
    Abstract: An improved platinum(IV) compound and its application as an antitumor agent are disclosed.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: July 2, 2002
    Assignee: AnorMED Inc.
    Inventors: Christen M. Gianomenico, Ernest S. Y. Wong