Abstract: A system for the delivery of therapeutic substances to cavities of a patient. The system can include a handpiece tool coupled with a pump. The handpiece tool can include a shaft including a first portion of a channel coupled to a multi-input tubing. The handpiece tool can include an angled portion coupled with the shaft. The handpiece tool can include a second portion of the channel, wherein the angled portion positions a tip portion within a cavity, wherein the tip portion projects from the angled portion and includes an outlet and a third portion of the channel. The handpiece tool can include a collar a distance from the outlet, the collar configured to control a distance the tip portion projects. The handpiece tool can include a mixing chamber configured to receive the components of the drug and output the mixed drug via the third portion of the channel.

Abstract: The present disclosure describes a system for the delivery of therapeutic substances to the cavities of a patient. The system can include a wearable micropump that is fluidically coupled with a handpiece. The handpiece can be inserted, for example, into the middle ear via a surgical tympanotomy approach. The system can enable a controlled injection of a therapeutic substance directly into the patient's cavity.

Abstract: The present disclosure describes a system for the delivery of therapeutic substances to the cavities of a patient. The system can include a wearable micropump that is fluidically coupled with a handpiece. The handpiece can be inserted, for example, into the middle ear via a surgical tympanotomy approach. The system can enable a controlled injection of a therapeutic substance directly into the patient's cavity.

Abstract: A system for the delivery of therapeutic substances to cavities of a patient. The system can include a handpiece tool coupled with a pump. The handpiece tool can include a shaft including a first portion of a channel coupled to a multi-input tubing. The handpiece tool can include an angled portion coupled with the shaft. The handpiece tool can include a second portion of the channel, wherein the angled portion positions a tip portion within a cavity, wherein the tip portion projects from the angled portion and includes an outlet and a third portion of the channel. The handpiece tool can include a collar a distance from the outlet, the collar configured to control a distance the tip portion projects. The handpiece tool can include a mixing chamber configured to receive the components of the drug and output the mixed drug via the third portion of the channel.

Abstract: The present disclosure describes a system for the delivery of therapeutic substances to the cavities of a patient. The system can include a wearable micropump that is fluidically coupled with a handpiece. The handpiece can be inserted, for example, into the middle ear via a surgical tympanotomy approach. The system can enable a controlled injection of a therapeutic substance directly into the patient's cavity.

Abstract: A wire bonding tool for bonding a micro-coaxial wire to a bonding surface includes an electrical-energy application mechanism configured to apply electrical-energy to remove a portion of an electrically conductive shield layer of the micro-coaxial wire to expose a portion of an insulating layer of the micro-coaxial wire, a thermal-energy application mechanism configured to apply thermal-energy to the micro-coaxial wire to remove the exposed portion of the insulating layer of the micro-coaxial wire to expose a portion of a core wire of the micro-coaxial wire, and a bonding head configured to bond the exposed portion of the core wire of the micro-coaxial wire to the bonding surface.

Abstract: A wire fabrication apparatus includes a number of fluid channels, each fluid channel configured to receive a first portion of a corresponding wire of a number of wires and including a fluid flowing in a first direction therein. A twisting mechanism is configured for attachment to second portions of the number of wires, the twisting mechanism being configured to draw the number of wires from the number of fluid channels in a second direction opposite to the first direction and to twist the number of drawn wires. A controller controls twisting mechanism to form a twisted wire, including controlling the twisting mechanism to draw the number of wires from the number of fluid channels in the second direction and to twist the drawn wire.