Patents by Inventor Ernest W. Yankee
Ernest W. Yankee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4119651Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 10, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4119787Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 10, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4118579Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 3, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4118580Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 3, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4118581Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 3, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4118578Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: October 3, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4100355Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: June 28, 1973Date of Patent: July 11, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4097675Abstract: This invention is a group of 8-beta, 12-alpha -PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: February 23, 1976Date of Patent: June 27, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4096343Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostagiandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: February 23, 1976Date of Patent: June 20, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4096342Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: February 23, 1976Date of Patent: June 20, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4095036Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: February 23, 1976Date of Patent: June 13, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4088663Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: May 9, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4085271Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes at the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: March 3, 1977Date of Patent: April 18, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4084063Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: February 23, 1976Date of Patent: April 11, 1978Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 4026909Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.Type: GrantFiled: July 14, 1975Date of Patent: May 31, 1977Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 3987085Abstract: This invention is a group of 8-.beta., 12-.alpha.-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: October 29, 1974Date of Patent: October 19, 1976Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 3983165Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: October 29, 1974Date of Patent: September 28, 1976Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 3979439Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: October 29, 1974Date of Patent: September 7, 1976Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 3979438Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: October 29, 1974Date of Patent: September 7, 1976Assignee: The Upjohn CompanyInventor: Ernest W. Yankee
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Patent number: 3979435Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.Type: GrantFiled: October 29, 1974Date of Patent: September 7, 1976Assignee: The Upjohn CompanyInventor: Ernest W. Yankee