Patents by Inventor Ernest W. Yankee

Ernest W. Yankee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4119651
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 10, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4119787
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 10, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4118579
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4118580
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4118581
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4118578
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4100355
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: June 28, 1973
    Date of Patent: July 11, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4097675
    Abstract: This invention is a group of 8-beta, 12-alpha -PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: June 27, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4096343
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostagiandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: June 20, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4096342
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: June 20, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4095036
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: June 13, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4088663
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: May 9, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4085271
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes at the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: April 18, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4084063
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: February 23, 1976
    Date of Patent: April 11, 1978
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 4026909
    Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
    Type: Grant
    Filed: July 14, 1975
    Date of Patent: May 31, 1977
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 3987085
    Abstract: This invention is a group of 8-.beta., 12-.alpha.-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: October 19, 1976
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 3983165
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: September 28, 1976
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 3979439
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: September 7, 1976
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 3979438
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: September 7, 1976
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee
  • Patent number: 3979435
    Abstract: This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: September 7, 1976
    Assignee: The Upjohn Company
    Inventor: Ernest W. Yankee