Patents by Inventor Ernesto J. Muñoz

Ernesto J. Muñoz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180362599
    Abstract: The present disclosure describes analog conotoxin peptides of the ?-conotoxin peptide RgIA. These analog conotoxin peptides block the ?9?10 subtype of the nicotinic acetylcholine receptor (nAChR) and can be used for treating pain and inflammation including inflammatory pain, cancer related pain, and neuropathic pain. The RgIA analogs described in the present invention include a variety of sequence modifications and chemical modifications that are introduced to improve the drug-like characteristics of RgIA analogs and thereby increase their therapeutic value.
    Type: Application
    Filed: November 6, 2015
    Publication date: December 20, 2018
    Applicant: Kineta Chronic Pain, LLC
    Inventors: Jeffrey Jerard Posakony, Ernesto J. Munoz
  • Patent number: 9937230
    Abstract: Disclosed herein are methods of treating ophthalmic conditions such as dry eye and uveitis by administering a pharmaceutical composition including a toxin-based therapeutic peptide. The peptide can include an acid or amide at the C-terminus and can be attached to an organic or inorganic chemical entity that has an anionic charge.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: April 10, 2018
    Assignee: Kineta One, LLC
    Inventors: Shawn P. Iadonato, Ernesto J. Munoz
  • Publication number: 20160338967
    Abstract: Depot formulations including therapeutic proteins are provided. The therapeutic proteins can be toxin-based therapeutic proteins. The depot formulations release the therapeutic protein within sustained effective levels for at least one month following a single administration. The toxin-based therapeutic proteins can include ShK-based proteins.
    Type: Application
    Filed: December 23, 2014
    Publication date: November 24, 2016
    Applicant: KINETA ONE, LLC
    Inventors: Shawn P. IADONATO, Ernesto J. MUNOZ, James CHESKO, Eric J. TARCHA
  • Publication number: 20160000869
    Abstract: Disclosed herein are methods of treating immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) comprising administering a toxin-based therapeutic peptide, such as an ShK-based peptide. The peptide can include an acid or amide at the C-terminus and/or the peptide can be attached to an organic or inorganic chemical entity that has an anionic charge.
    Type: Application
    Filed: March 5, 2014
    Publication date: January 7, 2016
    Inventors: Shawn P. Iadonato, Ernesto J. Munoz
  • Publication number: 20150342932
    Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
    Type: Application
    Filed: June 8, 2015
    Publication date: December 3, 2015
    Inventors: Shawn P. Iadonato, Kristin M. Bedard, Ernesto J. Munoz, Myra Wang Imanaka, Kerry W. Fowler
  • Patent number: 9073946
    Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: July 7, 2015
    Assignee: Kineta, Inc.
    Inventors: Shawn P. Iadonato, Kristin M. Bedard, Ernesto J. Muñoz, Myra W. Imanaka, Kerry W. Fowler
  • Publication number: 20140199348
    Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
    Type: Application
    Filed: February 12, 2013
    Publication date: July 17, 2014
    Applicant: KINETA, INC.
    Inventors: Shawn P. Iadonato, Kristin M. Bedard, Ernesto J. Muñoz, Myra W. Imanaka, Kerry W. Fowler