Patents by Inventor Ernesto Simon

Ernesto Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improved production of rebaudioside D and rebaudioside M
    Patent number: 10612066
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 7, 2020
    Assignee: Evolva SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20200017896
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: June 7, 2019
    Publication date: January 16, 2020
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Recombinant production of steviol glycosides
    Patent number: 10435730
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: October 8, 2019
    Assignee: EVOLVA SA
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Hansen Halkjaer, Ernesto Simon, Sabina De Andrade Periera Tavares
  • Production of steviol glycoside in recombinant hosts
    Patent number: 10364450
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 30, 2019
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
    Publication number: 20190203243
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 4, 2019
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Biosynthesis of phenylpropanoids and phenylpropanoid derivatives
    Patent number: 10294499
    Abstract: Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia lyase from Aeromonas salmonicida A449 provides improved coumaric acid production.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: May 21, 2019
    Assignee: EVOLVA SA
    Inventors: Ernesto Simon Vecilla, Beata Joanna Lehka, Carlos Casado Vazquez
  • Efficient Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20180371517
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
    Type: Application
    Filed: June 7, 2018
    Publication date: December 27, 2018
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • Efficient production of steviol glycosides in recombinant hosts
    Patent number: 10017804
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: July 10, 2018
    Assignee: EVOLVA SA
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • BIOSYNTHESIS OF PHENYLPROPANOIDS AND PHENYLPROPANOID DERIVATIVES
    Publication number: 20180163235
    Abstract: Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia lyase from Aeromonas salmonicida A449 provides improved coumaric acid production.
    Type: Application
    Filed: May 27, 2016
    Publication date: June 14, 2018
    Inventors: Ernesto SIMON VECILLA, Beata Joanna LEHKA, Carlos Casado VAZQUEZ
  • A METHOD FOR PRODUCING RESVERATROL
    Publication number: 20180155733
    Abstract: Recombinant hosts and methods for producing resveratrol in recombinant hosts are disclosed herein.
    Type: Application
    Filed: May 12, 2016
    Publication date: June 7, 2018
    Inventors: Ernesto SIMON VECILLA, Carlos Casado VAZQUEZ, Niels Bjerg JENSEN
  • Biosynthesis of Phenylpropanoid and Dihydrophenylpropanoid Derivatives
    Publication number: 20180142216
    Abstract: Provided herein are methods and compositions for producing phenylpropanoid derivatives, such as chalcones and stilbenes, and dihydrophenylpropanoid derivatives, such as dihydrochalcones and dihydrostilbenes, in microorganisms. In particular, the disclosure provides recombinant microorganisms and methods of use thereof for producing phenylpropanoid derivative compounds and dihydrophenylpropanoid derivative compounds.
    Type: Application
    Filed: June 6, 2016
    Publication date: May 24, 2018
    Inventors: Michael NAESBY, Ernesto SIMÓN VECILLA, Michael EICHENBERGER, Beata Joanna LEHKA, Walden Emil BJØRN-YOSHIMOTO, Niels Bjerg JENSEN, Jane Dannow DYEKJÆR
  • Methods for improved production of Rebaudioside D and Rebaudioside M
    Patent number: 9957540
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided herein.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: May 1, 2018
    Assignee: EVOLVA SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20170369922
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: January 29, 2016
    Publication date: December 28, 2017
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Recombinant Production of Steviol Glycosides
    Publication number: 20170321238
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: February 22, 2017
    Publication date: November 9, 2017
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Halkjaer Hansen, Ernesto Simon, Sabina Tavares
  • Pet transport
    Patent number: 9781900
    Abstract: A deployable pet carrier assembly for a vehicle includes a sliding rail guide system configured to attach the pet carrier to a vehicle seat back and collapsible front, rear, and side walls defining a box structure when deployed. An actuator is provided, configured to retain or release the pet carrier walls for transitioning the pet carrier between a collapsed configuration and a deployed configuration. The sliding guide rail system includes front and rear guide rails configured to slidingly hold the pet carrier front wall and rear wall. A tray may be included to define a floor of the pet carrier.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: October 10, 2017
    Assignee: Ford Global Technologies, LLC
    Inventors: Eric Vargas Iinan, Edgardo F. Ortiz Hernandez, Jose Ernesto Simon Gonzalez
  • Recombinant production of steviol glycosides
    Patent number: 9631215
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: April 25, 2017
    Assignee: EVOLVA SA
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Hansen Halkjaer, Ernesto Simon, Sabina De Andrade Periera Tavares
  • PET TRANSPORT
    Publication number: 20160353707
    Abstract: A deployable pet carrier assembly for a vehicle includes a sliding rail guide system configured to attach the pet carrier to a vehicle seat back and collapsible front, rear, and side walls defining a box structure when deployed. An actuator is provided, configured to retain or release the pet carrier walls for transitioning the pet carrier between a collapsed configuration and a deployed configuration. The sliding guide rail system includes front and rear guide rails configured to slidingly hold the pet carrier front wall and rear wall. A tray may be included to define a floor of the pet carrier.
    Type: Application
    Filed: June 4, 2015
    Publication date: December 8, 2016
    Inventors: Eric Vargas linan, Edgardo F. Ortiz Hernandez, Jose Ernesto Simon Gonzalez
  • METHOD FOR PRODUCING MODIFIED RESVERATROL
    Publication number: 20160215306
    Abstract: Methods for producing glycosylated and methylated resveratrol in a genetically engineered cell, by bioconversion, and in vitro are disclosed herein.
    Type: Application
    Filed: August 15, 2014
    Publication date: July 28, 2016
    Applicant: Evolva SA
    Inventors: Richard Jan Steven Baerends, Ernesto Simon, Jean Phillippe Meyer, Carlos Casado Vazquez
  • METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
    Publication number: 20160186225
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Application
    Filed: February 6, 2014
    Publication date: June 30, 2016
    Applicant: Evolva SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Frederico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Efficient Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20150361476
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
    Type: Application
    Filed: February 11, 2014
    Publication date: December 17, 2015
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin