Patents by Inventor Ernesto Soto-Priante

Ernesto Soto-Priante has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230226171
    Abstract: An active or inactivated recombinant vaccine against COVID-19 is described that comprises a Newcastle disease viral vector and a pharmaceutically acceptable carrier, adjuvant and/or excipient, characterized in that the viral vector is a virus capable of generating a cellular immune response that has a SARS-CoV-2 exogenous nucleotide sequence inserted,
    Type: Application
    Filed: February 22, 2021
    Publication date: July 20, 2023
    Inventors: Bernardo LOZANO-DUBERNARD, Ernesto SOTO-PRIANTE, David SARFATI-MIZRAHI, Felipa CASTRO-PERALTA, Georgina PAZ-DE LA ROSA, Peter PALESE, Adolfo GARCIA-SASTRE, Florian KRAMMER, Weina SUN
  • Patent number: 10758608
    Abstract: A recombinant vaccine comprising a serotype 9 fowl adenovirus vector (FAdV-9) having at least one exogenous nucleotide sequence inserted encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region, and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the at least one exogenous nucleotide sequence encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region is located between the 491 and 2782 nucleotides. The vector of this vaccine is stable for industrial scale production. When administering this vaccine in combination with a vaccine against Marek's disease, both vaccines produce an adequate immune response which is not affected by interference between each other. In the same way, effectiveness of the recombinant vaccine is not affected by maternal antibodies, and is capable of inducing both an early and lasting protective response, even with only one application.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: September 1, 2020
    Assignee: GRUPO INDUSTRIAL PECUARIO, S.A. DE C.V.
    Inventors: Bernardo Lozano-Dubernard, Ernesto Soto-Priante, David Sarfati-Mizrahi
  • Patent number: 10201602
    Abstract: A live or inactivated recombinant vaccine is described, comprising a viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the viral vector is capable of generating a cell immune response due to an increased alpha and/or gamma interferon production, and is capable of a quick replication, and it has inserted a nucleotide sequence of the ORF 5 and ORF 6 from PRSS.
    Type: Grant
    Filed: May 7, 2011
    Date of Patent: February 12, 2019
    Assignee: LABORATORIO AVI-MEX, S.A. DE C.V.
    Inventors: Bernardo Lozano-Dubernard, Ernesto Soto-Priante, David Sarfati-Mizrahi, Jesús Horacio Lara-Puente
  • Publication number: 20170232096
    Abstract: A recombinant vaccine comprising a serotype 9 fowl adenovirus vector (FAdV-9) having at least one exogenous nucleotide sequence inserted encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region, and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the at least one exogenous nucleotide sequence encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region is located between the 491 and 2782 nucleotides. The vector of this vaccine is stable for industrial scale production. Likewise, even when administering this vaccine in combination with a vaccine against Marek's disease, both vaccines produce an adequate immune response which is not affected by interference between each other. In the same way, effectiveness of the recombinant vaccine is not affected by maternal antibodies, and is capable of inducing both an early and lasting protective response, even with only one application.
    Type: Application
    Filed: August 6, 2015
    Publication date: August 17, 2017
    Inventors: Bernardo LOZANO-DUBERNARD, Ernesto SOTO-PRIANTE, David SARFATI-MIZRAHI
  • Publication number: 20150056245
    Abstract: A vaccine is described, comprising an inactivated viral vector having inserted an exogenous nucleotide sequence coding for a disease of concern; and, a pharmaceutically acceptable vehicle, adjuvant or excipient, which provides due protection against the disease of concern by using a viral vector titer similar to that required for an active-virus vaccine based on the same viral vector. Mainly, viral vectors of paramixovirus or adenovirus are described.
    Type: Application
    Filed: September 3, 2014
    Publication date: February 26, 2015
    Inventors: Bernardo LOZANO-DUBERNARD, David Sarfati-Mizrahi, Jesús Alejandro Suárez-Martínez, Manuel Joaquín Gay-Gutiérrez, Ernesto Soto-Priante
  • Publication number: 20140199343
    Abstract: A live or inactivated recombinant vaccine is described, comprising a viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the viral vector is capable of generating a cell immune response due to an increased alpha and/or gamma interferon production, and is capable of a quick replication, and it has inserted a nucleotide sequence of the ORF 5 and ORF 6 from PRSS.
    Type: Application
    Filed: May 7, 2011
    Publication date: July 17, 2014
    Applicant: LABORATORIO AVI-MEX, S.A. DE C.V.
    Inventors: Bernardo Lozano-Dubernard, Ernesto Soto-Priante, David Sarfati-Mizrahi, Jesús Horacio Lara-Puente
  • Publication number: 20110311578
    Abstract: A vaccine is described, comprising an inactivated viral vector having inserted an exogenous nucleotide sequence coding for a disease of concern; and, a pharmaceutically acceptable vehicle, adjuvant or excipient, which provides due protection against the disease of concern by using a viral vector titer similar to that required for an active-virus vaccine based on the same viral vector. Mainly, viral vectors of paramixovirus or adenovirus are described.
    Type: Application
    Filed: May 19, 2011
    Publication date: December 22, 2011
    Applicant: LABORATORIO AVI-MEX, S.A. DE C.V.
    Inventors: Bernardo LOZANO-DUBERNARD, David Sarfati-Mizrahi, Jesús Alejandro Suárez-Martínez, Manuel Joaquin Gay-Gutierrez, Ernesto Soto-Priante