Patents by Inventor Ernst Binderup

Ernst Binderup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070255066
    Abstract: The present invention relates to processes for epimerising alcohols of compounds having a hydroxyl substituent on an asymmetric allylic carbon, such as compounds useful for the synthesis of vitamin D analogues where the epimeric hydroxyl substituent is at the 24 position. The Invention further relates to methods of producing intermediates useful for the synthesis of calcipotriol by said epimerisation processes.
    Type: Application
    Filed: August 22, 2005
    Publication date: November 1, 2007
    Applicant: Leo Pharma A/S
    Inventors: Hendrik Pedersen, Claus Age Bretting, Ernst Binderup
  • Publication number: 20070249676
    Abstract: Pyridyl cyanoguanidine compounds of the general formula I wherein A, X1, X2, X3, Y1, Y2, Y3, R1, R2, R5, R6 and n are as indicated in the description are suitable as prodrugs in human and veterinary therapy of proliferative diseases such as cancers.
    Type: Application
    Filed: June 28, 2007
    Publication date: October 25, 2007
    Applicant: LEO Pharma A/S
    Inventors: Ernst Binderup, Tore Duvold
  • Publication number: 20060166949
    Abstract: Compounds according to formula I in which formula R1 and R2, which may be the same or different, represent halogen, (C1-C6)hydrocarbyl, optionally substituted with one or two hydroxyl group or one or more fluorine atoms, or, together with the carbon atom to which they are both attached, R1 and R2 form a (C3-C6)carbocyclic ring, or one of R1 and R2 taken together with R3 forms a direct bond, such that a triple bond is constituted, or R1 and R2 represent both hydrogen; R3 when not forming a direct bond with one of R1 and R2 represents hydrogen or (C1-C3)hydrocarbyl; X represents (E)-ethylene, (Z)-ethylene, ethynylene, or a bond; Y and Z independently represent hydrogen or methyl; the bond between C#16 and C#17 is depicted with a dotted line to illustrate that said bond may be either a single bond, in which case the projection of the ring substituent is beta, or a double bond; A represents hydroxyl, fluorine or hydrogen; B represents CH2 or H2; the configuration in the 3-position corresponds to the same c
    Type: Application
    Filed: October 23, 2003
    Publication date: July 27, 2006
    Applicant: Leo Pharma A/S
    Inventors: Ernst Binderup, Holst Kai, Aage Svensgaard Claus, John Martin
  • Publication number: 20060014804
    Abstract: Pyridyl cyanoguanidine compounds according to formula I wherein A, R1, R2, R5, R6, X1, X2, X3, X4, Y1, Y2, Y3, Y4 and n are as indicated in the description are useful as prodrugs in human veterinary therapy of proliferative diseases such as cancers.
    Type: Application
    Filed: May 15, 2003
    Publication date: January 19, 2006
    Applicant: Leo Pharma A/S
    Inventor: Ernst Binderup
  • Publication number: 20050215588
    Abstract: Pyridyl cyanoguanidine compounds of the general formula I wherein A, X1, X2, X3, Y1, Y2, Y3, R1, R2, R5, R6 and n are as indicated in the description are suitable as prodrugs in human and veterinary therapy of proliferative diseases such as cancers.
    Type: Application
    Filed: May 15, 2003
    Publication date: September 29, 2005
    Applicant: Leo Pharma A/S
    Inventors: Ernst Binderup, Tore Duvold
  • Patent number: 6525077
    Abstract: A compound of the formula is disclosed, the compound being suited for therapeutical uses. The invention also discloses compositions comprising said compound, methods of treatment involving administering said compound to a patient, and the use of said compound in the manufacture of medicaments.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: February 25, 2003
    Assignee: Leo Pharmaceutical Products Ltd. A/S
    Inventors: Ernst Binderup, Pernille-Julia Vig Hjarnaa
  • Publication number: 20020165201
    Abstract: The invention relates to compounds of the formula I 1
    Type: Application
    Filed: November 20, 2001
    Publication date: November 7, 2002
    Inventors: Ernst Binderup, Pernille-Julia Vig Hjarnaa