Patents by Inventor Ernst H. K. Stelzer
Ernst H. K. Stelzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230347580Abstract: The present invention refers to a device and method for stereolithograpic three dimensional (3D) printing comprising: a) a container adequate for containing a photopolymerizable polymer, b) at least one laser generator emitting a light beam with a wavelength between 360 nm and 1000 nm, c) modulation means for modulating said light beam into at least two light sheets which are matrices of light, and d) means for irradiating said light sheets in the container containing said photopolymerizable polymer; wherein said at least one laser generator is arranged so that said at least two light sheets are crossed inside said container, leading to polymerization of the photopolymerizable polymer at the crossing of said light sheets.Type: ApplicationFiled: August 9, 2021Publication date: November 2, 2023Inventors: ELENA MARTÍNEZ FRAIZ, NÚRIA TORRAS ANDRÉS, FRANCESCO PAMPALONI, ERNST H. K. STELZER, GUSTAF MÅRTENSSON, ROBERT EKLUND, NUR ISMAIL
-
Publication number: 20210278649Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: ApplicationFiled: May 21, 2021Publication date: September 9, 2021Applicant: European Molecular Biology LaboratoryInventor: Ernst H.K. Stelzer
-
Patent number: 11042015Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: GrantFiled: November 20, 2017Date of Patent: June 22, 2021Assignee: European Molecular Biology LaboratoryInventor: Ernst H. K. Stelzer
-
Publication number: 20200165556Abstract: A cover lid collector (10) for a sample carrier (40) for cell cultivation, wherein the cover lid collector (10) comprises a connecting portion (12) for engaging with the sample carrier (40) for closing the same, wherein the connecting portion (12) defines a first plane (11). The cover lid collector (10) further comprises a cavity (14), which when the cover lid collector is engaged with the sample carrier (40), has a cross-section that decreases in a direction perpendicular to the first plane (11) and pointing away from said sample carrier (40) between a near end (16) of the cavity (14) and a far end (18) of the cavity (14), wherein the near end (16) is closer to the sample carrier (40) than the far end (18).Type: ApplicationFiled: May 17, 2018Publication date: May 28, 2020Inventors: Katharina Hötte-Lohmeier, Francesco Pampaloni, Ernst H. K. Stelzer
-
Publication number: 20180088304Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: ApplicationFiled: November 20, 2017Publication date: March 29, 2018Applicant: Europaeisches Laboratorium Fuer Molekularbiologie (EMBL)Inventor: Ernst H.K. Stelzer
-
Patent number: 9857577Abstract: A microscope and imaging method in which a layer of the sample is illuminated by a thin strip of light and the sample is viewed perpendicular to the plane of the strip of light. The depth of the strip of light thus essentially determines the depth of focus of the system. To record the image, the object is displaced through the strip of light, which remains fixed in relation to the detector, and fluorescent and/or diffused light is captured by a planar detector. Objects that absorb or diffuse a large amount of light are viewed from several spatial directions. The three-dimensional images, which are captured from each direction can be combined retrospectively to form one image, in which the data is weighted according to its resolution. The resolution of the combined image is then dominated by the lateral resolution of the individual images.Type: GrantFiled: January 22, 2013Date of Patent: January 2, 2018Assignee: European Molecular Biology Laboratory (EMBL)Inventors: Ernst H. K. Stelzer, Sebastian Enders, Jan Huisken, Steffen Lindek, James H. Swoger
-
Patent number: 9823455Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: GrantFiled: February 3, 2015Date of Patent: November 21, 2017Assignee: Europaeisches Laboratorium Fuer Molekularbiologie (EMBL)Inventor: Ernst H. K. Stelzer
-
Patent number: 9816916Abstract: A capillary cell is described along with an arrangement and a method for receiving, positioning and examining a microscopic specimen, in particular a cleared fluorescent specimen with the help of a single-plane fluorescence microscope. The capillary cell is suitable for being positioned in a chamber volume and contains a capillary section, which comprises a wall. The wall encloses a specimen volume and is planar and transparent in at least some sections. In addition, the capillary cell includes an upper and a lower closure section, which are connected to the capillary section and which seal the capillary section. The specimen volume is separated from the chamber volume by the capillary section, the upper closure section and the lower closure section.Type: GrantFiled: September 3, 2013Date of Patent: November 14, 2017Assignee: Johann Wolfgang Goethe-UniversitaetInventors: Francesco Pampaloni, Ernst H. K. Stelzer, Christian Mattheyer
-
Publication number: 20150309294Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: ApplicationFiled: February 3, 2015Publication date: October 29, 2015Applicant: Europaeisches Laboratorium Fuer Molekularbiologie (EMBL)Inventor: Ernst H.K. STELZER
-
Publication number: 20150211981Abstract: A capillary cell is described along with an arrangement and a method for receiving, positioning and examining a microscopic specimen, in particular a cleared fluorescent specimen with the help of a single-plane fluorescence microscope. The capillary cell is suitable for being positioned in a chamber volume and contains a capillary section, which comprises a wall. The wall encloses a specimen volume and is planar and transparent in at least some sections. In addition, the capillary cell includes an upper and a lower closure section, which are connected to the capillary section and which seal the capillary section. The specimen volume is separated from the chamber volume by the capillary section, the upper closure section and the lower closure section.Type: ApplicationFiled: September 3, 2013Publication date: July 30, 2015Inventors: Francesco Pampaloni, Ernst H. K. Stelzer, Christian Mattheyer
-
Patent number: 8970950Abstract: The invention relates to a microscope in which a layer of the sample is illuminated by a plurality of thin strips of light (11) passed through a grid (34) and the sample is viewed (5) perpendicular to the plane of the strips of light. To record the image, the object (4) is displaced through the strips of light (11). At least three different images of the objects (4) are made at different phase angles. The images can be combined to form a single combined image.Type: GrantFiled: November 3, 2006Date of Patent: March 3, 2015Assignee: Europaeisches Laboratorium fuer Molekularbiologie (Embl)Inventor: Ernst H. K. Stelzer
-
Publication number: 20140042339Abstract: A microscope and imaging method in which a layer of the sample is illuminated by a thin strip of light and the sample is viewed perpendicular to the plane of the strip of light. The depth of the strip of light thus essentially determines the depth of focus of the system. To record the image, the object is displaced through the strip of light, which remains fixed in relation to the detector, and fluorescent and/or diffused light is captured by a planar detector. Objects that absorb or diffuse a large amount of light are viewed from several spatial directions. The three-dimensional images, which are captured from each direction can be combined retrospectively to form one image, in which the data is weighted according to its resolution. The resolution of the combined image is then dominated by the lateral resolution of the individual images.Type: ApplicationFiled: January 22, 2013Publication date: February 13, 2014Applicant: EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL)Inventors: Ernst H.K. Stelzer, Sebastian Enders, Jan Huisken, Steffen Lindek, James H. Swoger
-
Publication number: 20090225413Abstract: The invention relates to a microscope, in which a layer of the sample is illuminated by a thin strip of light (11) and the sample is viewed (5) perpendicular to the plane of the strip of light. The depth of the strip of light (11) thus essentially determines the depth of focus of the system. To record the image, the object (4) is displaced through the strip of light (11), which remains fixed in relation to the detector (8), and fluorescent and/or diffused light is captured by a planar detector. Objects (4) that absorb or diffuse a large amount of light are viewed from several spatial directions. The three-dimensional images, which are captured from each direction can be combined retrospectively to form one image, in which the data is weighted according to its resolution. The resolution of the combined image is then dominated by the lateral resolution of the individual images.Type: ApplicationFiled: May 19, 2009Publication date: September 10, 2009Applicant: EUROPAEISCHES Laboratorium fuer Molekularbiologie (EMBL)Inventors: Ernst H.K. Stelzer, Sebastian Enders, Jan Huisken, Steffen Lindek, James H. Swoger
-
Patent number: 7554725Abstract: The invention relates to a microscope, in which a layer of the sample is illuminated by a thin strip of light (11) and the sample is viewed (5) perpendicular to the plane of the strip of light. The depth of the strip of light (11) thus essentially determines the depth of focus of the system. To record the image, the object (4) is displaced through the strip of light (11), which remains fixed in relation to the detector (8), and fluorescent and/or diffused light is captured by a planar detector. Objects (4) that absorb or diffuse a large amount of light are viewed from several spatial directions. The three-dimensional images, which are captured from each direction can be combined retrospectively to form one image, in which the data is weighted according to its resolution. The resolution of the combined image is then dominated by the lateral resolution of the individual images.Type: GrantFiled: June 6, 2003Date of Patent: June 30, 2009Assignee: Europaeisches Laboratorium fuer Molekularbiologie (EMBL)Inventors: Ernst H. K. Stelzer, Sebastian Enders, Jan Huisken, Steffen Lindek, James H. Swoger
-
Patent number: 6833923Abstract: A method for detecting an object and/or an object's ambience and/or an object's inner space using a scanning particle trapped within a trapping potential. The trapping potential is configured within a position range defined relative to the object or a reference point in a first position determining stage which is associated with a first order of magnitude. In a second position determining stage, which is associated with an order of magnitude less than that of the first order of magnitude, the scanning particle trapped within the trapping potential moves more or less freely in three-dimensions while scanning subjected to the trapping potential to scan the scan volume. A plurality of scanning particle positions assumed as a consequence of scanning are detected within the scan volume.Type: GrantFiled: November 15, 2001Date of Patent: December 21, 2004Assignee: Europaisches Laboratorium fur Molekularbiologie (EMBL)Inventors: Ernst-Ludwig Florin, Heinrich J. K. Hörber, Ernst H. K. Stelzer
-
Publication number: 20030076587Abstract: A confocal microscope with separate illumination and detection directions is disclosed. The detection direction in the object is inclined relative to the illumination direction at a predetermined angle which is selected such that the overlapping area of the illumination volume and detection volume is reduced compared to a conventional confocal microscope. A beam splitter or a reflector is provided in the beam path between the objective and an image plane of the microscope for coupling in the illumination light and/or for coupling out the detection light and/or in that the illumination light is coupled into the microscope and/or the detection light is coupled out of the microscope via one or more light-conducting fibers.Type: ApplicationFiled: November 25, 2002Publication date: April 24, 2003Applicant: Carl Zeiss Jena GmbHInventors: Ernst H. K. Stelzer, Thomas Stefany, Steffen Lindek, Jim Swoger
-
Publication number: 20020063868Abstract: A method for detecting an object and/or an object's ambience and/or an object's inner space using a scanning particle trapped within a trapping potential. The trapping potential is configured within a position range defined relative to the object or a reference point in a first position determining stage which is associated with a first order of magnitude. In a second position determining stage, which is associated with an order of magnitude less than that of the first order of magnitude, the scanning particle trapped within the trapping potential moves more or less freely in three-dimensions while scanning subjected to the trapping potential to scan the scan volume. A plurality of scanning particle positions assumed as a consequence of scanning are detected within the scan volume.Type: ApplicationFiled: November 15, 2001Publication date: May 30, 2002Inventors: Ernst-Ludwig Florin, Heinrich J. K. Horber, Ernst H. K. Stelzer
-
Patent number: 6064518Abstract: A beam deflecting unit for multiple-axis examination of specimens in a microscope is disclosed which, on the one hand, enables the illumination and/or observation of the specimen from several sides and, on the other hand, allows observation of the specimen at an angle to the illumination axis. The examination of the specimen is carried out with an available microscope and with the beam deflecting unit according to the invention which is located between the microscope objective and the focal plane.Type: GrantFiled: July 28, 1998Date of Patent: May 16, 2000Assignee: Carl Zeiss Jena GmbHInventors: Ernst H. K. Stelzer, Steffen Lindek
-
Patent number: 5969854Abstract: A double-objective system for a microscope, wherein an objective is provided for focusing object illumination light onto an object point and an objective is provided for collecting light that proceeds from the object point. The optical axes of the two objectives are inclined relative to one another, so that the observation direction and the illumination direction are at an angle relative to one another. The two objectives are combined at a shared holder to form a double-objective constructional unit for guiding light from an object illumination source through a light passage opening, wherein, further, a light deflection system is provided, which shapes the illumination beam path and/or the observation beam path in such a way that the observation light coming from the observation objective exits the double-objective constructional unit through the light passage opening. The double-objective constructional unit can therefore be used in a conventional microscope construction.Type: GrantFiled: May 21, 1998Date of Patent: October 19, 1999Assignee: Carl Zeiss Jena GmbHInventors: Ernst H. K. Stelzer, Steffen Lindek