Patents by Inventor Ernst Heinz
Ernst Heinz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952581Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: November 22, 2021Date of Patent: April 9, 2024Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20220162629Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: November 22, 2021Publication date: May 26, 2022Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Patent number: 11180769Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: July 11, 2019Date of Patent: November 23, 2021Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20190323024Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: July 11, 2019Publication date: October 24, 2019Inventors: Thorsten ZANK, Jörg BAUER, Petra CIRPUS, Amine ABBADI, Ernst HEINZ, Xiao QIU, Patricia VRINTEN, Petra SPERLING, Frederic DOMERGUE, Astrid SCHMIDT, Helene KIRSCH
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Patent number: 9624477Abstract: The present invention relates to nucleic acid sequences coding for polypeptides with ?-3-desaturase activity. The invention furthermore relates to nucleic acid constructs, vectors and organisms comprising at least one nucleic acid sequence according to the invention, at least one vector comprising the nucleic acid sequence and/or the nucleic acid constructs, and transgenic organisms comprise the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.Type: GrantFiled: January 9, 2013Date of Patent: April 18, 2017Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Thorsten Zank, Ernst Heinz
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Patent number: 9611441Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.Type: GrantFiled: May 2, 2014Date of Patent: April 4, 2017Assignee: BASF Plant Science GmbHInventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
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Publication number: 20170066994Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.Type: ApplicationFiled: May 2, 2014Publication date: March 9, 2017Applicant: BASF Plant Science GmbHInventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
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Publication number: 20170016015Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: August 16, 2016Publication date: January 19, 2017Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Patent number: 9433228Abstract: The invention relates to a method for the production of multiply-unsaturated fatty acids in an organism, into which nucleic acids have been introduced, which code for polypeptides with ?-5 elongase activity. Said nucleic acid sequences, optionally with further nucleic acid sequences, coding for polypeptides for the biosynthesis of fatty acids and lipid metabolism, are advantageously expressed in the organism. Nucleic acid sequences coding for a ?-6 desaturase, a ?-5 desaturase, ?-4 desaturase and/or ?-6 elongase activity are particularly advantageous and, advantageously, said saturases and elongases are derived from Thalassiosira, Euglena or Ostreococcus. The invention further relates to a method for the production of oils and/or triacylglycerides with an increased content of long-chain, multiply-unsaturated fatty acids.Type: GrantFiled: July 16, 2004Date of Patent: September 6, 2016Assignee: BASF Plant Science GmbHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Publication number: 20150170254Abstract: A system (100) and method for processing an electronic order is provided. The system comprises a remotely accessible server (102) having a first interface (108) with an ordering entity (106), a second interface (112) with a number of vendors (110), and a third interface (116) with a number of delivery providers (114). The server (102) is configured to receive an order placed by a consumer (104) with the ordering entity (106) through the first interface (108), transmit the order to a vendor (110) by means of the second interface (112) and once the order is ready for fulfillment, transmit a delivery instruction to a delivery provider (114) through the third interface (116). The server (102) is further configured to compute fees due to the vendor (110) and delivery provider (114), update a ledger account with the applicable amounts and, at regular intervals, transmit an instruction to a payment gateway (120) for settlement of the amounts due to each party.Type: ApplicationFiled: June 27, 2013Publication date: June 18, 2015Inventors: Ernst Heinz Van Biljon, Wessel Antonie Pieterse
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Patent number: 8933300Abstract: The invention relates to novel elongase genes with the sequences stated in sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or their homologs, derivatives or analogs, to a gene construct comprising this gene or its homologs, derivatives and analogs, and to its use. The invention also relates to vectors or transgenic organisms comprising an elongase gene with the sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or its homologs, derivatives and analogs. The invention furthermore relates to the use of the elongase gene sequences alone or in combination with further elongases and/or further fatty acid biosynthesis genes. The present invention relates to a novel elongase gene with the sequence SEQ ID NO:1 or its homologs, derivatives and analogs.Type: GrantFiled: March 5, 2007Date of Patent: January 13, 2015Assignee: BASF AktiengesellschaftInventors: Ernst Heinz, Thorsten Zank, Ulrich Zähringer, Jens Lerchl, Andreas Renz
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Patent number: 8835715Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic organism, preferably of a transgenic plant or of a transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?-6-desaturase [sic]. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of the unsaturated fatty acids or of the triglycerides with an increased content of unsaturated fatty acids prepared in the process.Type: GrantFiled: July 4, 2000Date of Patent: September 16, 2014Assignee: BASF Plant Science GmbHInventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa E Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
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Publication number: 20140235733Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.Type: ApplicationFiled: May 2, 2014Publication date: August 21, 2014Applicant: BASF Plant Science GmbHInventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
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Patent number: 8729337Abstract: The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention furthermore relates to the use of nucleic acid sequences SEQ ID NO: 1, 3, 5, 9, and 11 encoding polypeptides having desaturase or elongase activity in the method and for generating a transgenic organism, preferably a transgenic plant or a transgenic microorganism, with an increased content of fatty acids, oils or lipids with unsaturated C18-, C20-, or C22-fatty acids, and to their homologs or derivatives, to gene constructs encompassing these genes, and to their use alone or in combination with biosynthesis genes of polyunsaturated fatty acids. The invention also relates to multiexpression cassettes for seed-specific expression, and to vectors or organisms which encompass a desaturase gene alone or in combination with further desaturases and/or elongase genes or homologs using said expression cassettes.Type: GrantFiled: January 2, 2012Date of Patent: May 20, 2014Assignee: BASF Plant Science GmbHInventors: Jens Lerchl, Andreas Renz, Ernst Heinz, Frederic Domergue, Ulrich Zähringer
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Publication number: 20140026259Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: ApplicationFiled: June 7, 2013Publication date: January 23, 2014Inventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Patent number: 8486671Abstract: The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.Type: GrantFiled: April 2, 2009Date of Patent: July 16, 2013Assignee: BASF Plant Science GmbHInventors: Andreas Renz, Ernst Heinz, Amine Abbadi, Frederic Domergue, Thorsten Zank
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Patent number: 8373024Abstract: The present invention relates to nucleic acid sequences coding for polypeptides with ?-3-desaturase activity. The invention furthermore relates to nucleic acid constructs, vectors and organisms comprising at least one nucleic acid sequence according to the invention, at least one vector comprising the nucleic acid sequence and/or the nucleic acid constructs, and transgenic organisms comprise the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.Type: GrantFiled: April 27, 2010Date of Patent: February 12, 2013Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Thorsten Zank, Ernst Heinz
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Patent number: 8354569Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.Type: GrantFiled: July 28, 2010Date of Patent: January 15, 2013Assignee: University of BristolInventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
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Publication number: 20120210465Abstract: The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention furthermore relates to the use of nucleic acid sequences SEQ ID NO: 1, 3, 5, 9, and 11 encoding polypeptides having desaturase or elongase activity in the method and for generating a transgenic organism, preferably a transgenic plant or a transgenic microorganism, with an increased content of fatty acids, oils or lipids with unsaturated C18-, C20-, or C22-fatty acids, and to their homologs or derivatives, to gene constructs encompassing these genes, and to their use alone or in combination with biosynthesis genes of polyunsaturated fatty acids. The invention also relates to multiexpression cassettes for seed-specific expression, and to vectors or organisms which encompass a desaturase gene alone or in combination with further desaturases and/or elongase genes or homologs using said expression cassettes.Type: ApplicationFiled: January 2, 2012Publication date: August 16, 2012Applicant: BASF Plant Science GmbHInventors: Jens Lerchl, Andreas Renz, Ernst Heinz, Frederic Domergue, Ulrich Zähringer
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Patent number: 8088974Abstract: The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention furthermore relates to the use of nucleic acid sequences SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 11 encoding polypeptides having desaturase activity in the method and for generating a transgenic organism, preferably a transgenic plant or a transgenic microorganism, with an increased content of fatty acids, oils or lipids with unsaturated C18-, C20-, or C22-fatty acids, and to their homologs or derivatives, to gene constructs encompassing these genes, and to their use alone or in combination with biosynthesis genes of polyunsaturated fatty acids. The invention also relates to multiexpression cassettes for seed-specific expression, and to vectors or organisms which encompass a desaturase gene alone or in combination with further desaturases and/or elongase genes or homologs using said expression cassettes.Type: GrantFiled: September 24, 2009Date of Patent: January 3, 2012Assignee: BASF Plant Science GmbHInventors: Jens Lerchl, Andreas Renz, Ernst Heinz, Frederic Domergue, Ulrich Zähringer