Patents by Inventor Ernst Schottle

Ernst Schottle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel steroids of the pregnane series, substituted in the 17-position, their manufacture and their use
    Patent number: 4224320
    Abstract: Steroids of the formula ##STR1## wherein represents a single or double bond,X is hydrogen, fluorine or methyl;Y is hydrogen, hydroxy or alkanoyloxy of 1-6 carbon atoms;Z is hydrogen or methyl;V is methylene, ethylidene, hydroxymethylene or vinylidene; andR.sub.1 is alkyl of 1-6 carbon atoms or alkyl of 2-6 carbon atoms with an oxygen atom between two of the carbon atoms;R.sub.2 is hydrogen or alkyl of 1-6 carbon atoms, orR.sub.1 and R.sub.2 together form a tri- or tetramethylene group provided that Y is hydroxy or alkanoyloxy;have pharmacological activity and are useful as intermediates for preparing other pharmacologically active steroids.
    Type: Grant
    Filed: January 25, 1979
    Date of Patent: September 23, 1980
    Assignee: Schering, Aktiengesellschaft
    Inventors: Helmut Dahl, Ernst Schottle, Reinhold Wieske, Alfred Weber, Mario Kennecke
  • Novel 17-substituted 11 .beta.-hydroxy steroids of the pregnane series, their manufacture, preparation and use
    Patent number: 4207316
    Abstract: Corticoids of the formula ##STR1## wherein represents a single bond or a double bond;X is hydrogen, fluorine, chlorine or methyl;Y is hydrogen and Z is hydrogen, fluorine or chlorine, orY and Z together are a carbon-to-carbon bond;V is .beta.-hydroxymethylene, .beta.-chloromethylene or carbonyl;W is methylene, ethylidene or vinylidene;Q is oxygen or sulfur;R.sub.1 is alkyl of 1-8 carbon atoms, alkyl of 2-8 carbon atoms with an oxygen atom between two of the carbon atoms or benzyl, and R.sub.2 is hydrogen or alkyl of 1-4 carbon atoms, orR.sub.1 and R.sub.2 collectively are trimethylene or tetramethylene; andR.sub.3 is hydrogen, fluorine, chlorine, hydroxy, or hydroxy esterified by a C.sub.1-16 hydrocarbon carboxylic acid have valuable pharmacological properties, e.g., anti-inflammatory activity.
    Type: Grant
    Filed: January 25, 1979
    Date of Patent: June 10, 1980
    Assignee: Schering Aktiengesellschaft
    Inventors: Ernst Schottle, Alfred Weber, Mario Kennecke, Helmut Dahl, Joachim-Friedrich Kapp, Hans Wendt, Klaus Annen, Henry Laurent, Rudolf Wiechert