Patents by Inventor Ernst V. Arnold

Ernst V. Arnold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sterilization system and device
    Patent number: 9180217
    Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: November 10, 2015
    Assignee: NOXILIZER, INC.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
  • STERILIZATION SYSTEM AND DEVICE
    Publication number: 20150273095
    Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
    Type: Application
    Filed: August 18, 2014
    Publication date: October 1, 2015
    Inventors: Ernst V. ARNOLD, Blaine G. DOLETSKI, Thomas M. DUNN, Robert E. RAULLI, Edward P. MUELLER, Karen R. BENEDEK, Marie-Louise MURVILLE
  • Nitric oxide-releasing polymers
    Patent number: 8894985
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: November 25, 2014
    Assignee: Amulet Pharmaceuticals, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • Sterilization system and device
    Patent number: 8808622
    Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: August 19, 2014
    Assignee: Noxilizer, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
  • Nitric oxide-releasing molecules
    Patent number: 8101589
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: January 24, 2012
    Assignee: Noxilizer, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • STERILIZATION SYSTEM AND DEVICE
    Publication number: 20110318225
    Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
    Type: Application
    Filed: July 29, 2011
    Publication date: December 29, 2011
    Applicant: NOXILIZER, INC.
    Inventors: Ernst V. ARNOLD, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
  • Sterilization system and device
    Patent number: 8017074
    Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: September 13, 2011
    Assignee: Noxilizer, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
  • NITRIC OXIDE-RELEASING POLYMERS
    Publication number: 20110059036
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
    Type: Application
    Filed: November 5, 2010
    Publication date: March 10, 2011
    Inventors: Ernst V. ARNOLD, Blaine G. Doletski, Robert E. Raulli
  • Nitric oxide-releasing polymers
    Patent number: 7829553
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
    Type: Grant
    Filed: January 6, 2005
    Date of Patent: November 9, 2010
    Assignee: Amulet Pharmaceuticals, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • NITRIC OXIDE-RELEASING MOLECULES
    Publication number: 20090270509
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
    Type: Application
    Filed: July 2, 2009
    Publication date: October 29, 2009
    Applicant: Noxilizer, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • Nitric oxide-releasing molecules
    Patent number: 7569559
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: August 4, 2009
    Assignee: Noxilizer, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
    Patent number: 7348319
    Abstract: The present invention relates to nitric oxide-releasing amidine diazeniundiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: March 25, 2008
    Assignee: United States of America as represented by the Department of Health and Human Services
    Inventors: Joseph A Hrabie, Larry K Keefer, Ernst V Arnold
  • Nitric oxide-releasing imidate and thioimidate diazeniumdiolates
    Patent number: 7105502
    Abstract: The invention provides NO- or NO?-releasing imidate; and thioimidate, diazeniumdiolates, in which the N2O2? functional group is bonded to a carbon atom. The imidate and thioimidate diazeniumdiolates are bound to a polymer or a substrate.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: September 12, 2006
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Ernst V Arnold, Larry K Keefer, Joseph A Hrabie
  • Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
    Patent number: 6949530
    Abstract: The present invention relates to nitric oxide-releasing amidine diazeniumdiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: September 27, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Joseph A. Hrabie, Larry K. Keefer, Ernst V. Arnold
  • Novel nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
    Publication number: 20040092484
    Abstract: The invention provides NO- or NO−-releasing imidate, thioimidate, and amide diazeniumdiolates, in which the N2O2− functional group is bonded to a carbon atom. The invention also provides compositions comprising such diazeniumdiolate compounds, and methods of using such compounds and compositions. The invention further provides a method of preparing NO- or NO−-releasing imidate, thioimidate, and amide diazeniumdiolates.
    Type: Application
    Filed: November 6, 2003
    Publication date: May 13, 2004
    Applicant: Government of the United States of America, represented by the Secretary, Department of Health
    Inventors: Ernst V. Arnold, Larry K. Keefer, Joseph A. Hrabie
  • Novel nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
    Publication number: 20040014720
    Abstract: The present invention relates to nitric oxide-releasing amidine diazeniumdiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines.
    Type: Application
    Filed: July 18, 2002
    Publication date: January 22, 2004
    Applicants: Government of the United States of America, represented by the Secretary, Department of Health and Human Services
    Inventors: Joseph A. Hrabie, Larry K. Keefer, Ernst V. Arnold
  • Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
    Patent number: 6673338
    Abstract: The invention provides NO— or NO−-releasing imidate, thioimidate, and amide diazeniumdiolates, in which the N2O2− functional group is bonded to a carbon atom. The invention also provides compositions comprising such diazeniumdiolate compounds, and methods of using such compounds and compositions. The invention further provides a method of preparing NO— or NO−-releasing imidate, thioimidate, and amide diazeniumdiolates.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: January 6, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Ernst V. Arnold, Larry K. Keefer, Joseph A. Hrabie