Patents by Inventor Erwin Blomsma
Erwin Blomsma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11904024Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: GrantFiled: March 18, 2021Date of Patent: February 20, 2024Assignee: Aratana Therapeutics, Inc.Inventors: Nesya Goris, Johan Neyts, Erwin Blomsma, Stefaan Wera, Ainola Billiet, Joeri Auwerx, Veerle Debeurme, Maryline Roe, Pascal Puig
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Publication number: 20210205478Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: ApplicationFiled: March 18, 2021Publication date: July 8, 2021Inventors: Nesya GORIS, Johan NEYTS, Erwin BLOMSMA, Stefaan WERA, Ainola BILLIET, Joeri AUWERX, Veerle DEBEURME, Maryline ROE, Pascal PUIG
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Patent number: 10967074Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: GrantFiled: August 17, 2015Date of Patent: April 6, 2021Assignee: ARATANA THERAPEUTICS, INC.Inventors: Nesya Goris, Johan Neyts, Erwin Blomsma, Stefaan Wera, Ainola Billiet, Joeri Auwerx, Veerle Debeurme, Maryline Roe, Pascal Puig
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Publication number: 20150352118Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: ApplicationFiled: August 17, 2015Publication date: December 10, 2015Applicant: ARATANA THERAPEUTICS NVInventors: Nesya GORIS, Johan NEYTS, Erwin BLOMSMA, Stefaan WERA, Ainola BILLIET, Joeri AUWERX, Veerle DEBEURME, Maryline ROE, Pascal PUIG
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Patent number: 9107943Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: GrantFiled: January 20, 2012Date of Patent: August 18, 2015Assignee: ARATANA THERAPEUTICS NVInventors: Nesya Goris, Johan Neyts, Erwin Blomsma, Stefaan Wera, Ainola Billiet, Joeri Auwerx, Veerle Debeurme, Maryline Roe, Pascal Puig
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Patent number: 9040699Abstract: The present invention relates to the preparation of cyclopropane derivatives, in particular 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-4,8-dihydro-1H-purin-6-one, especially via the [(1S,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methanol intermediate.Type: GrantFiled: November 10, 2011Date of Patent: May 26, 2015Assignee: Aratana Therapeutics NVInventors: Eleonora Kiss, Erwin Blomsma, Serge De Bruijn, E. J. N. Remy Litjens
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Publication number: 20150098904Abstract: The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.Type: ApplicationFiled: January 20, 2012Publication date: April 9, 2015Applicant: ARATANA THERAPEUTICS NVInventors: Nesya Goris, Johan Neyts, Erwin Blomsma, Stefaan Wera, Ainola Billiet, Joeri Auwerx, Veerle Debeurme, Maryline Roe, Pascal Puig
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Publication number: 20150051394Abstract: The present invention relates to the preparation of cyclopropane derivatives, in particular 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-4,8-dihydro-1H-purin-6-one, especially via the [(1S,7R)-4-phenyl-3,5-dioxabicyclo[5.1.0]octan-1-yl]methanol intermediate.Type: ApplicationFiled: November 10, 2011Publication date: February 19, 2015Applicant: ARATANA THERAPEUTICS NVInventors: Eleonora Kiss, Erwin Blomsma, Serge De Bruijn, E.J.N. Remy Litjens
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Publication number: 20150018427Abstract: The present invention relates to compounds for use in a method for the treatment or prevention of parvovirus infections in humans and warm-blooded animals, including feline panleukopenia virus (FPV) infections in felids, canine parvovirus type 2 (CPV-2) infections in canines, minute virus of mice (MVM) infections in mice and B19 parvovirus infections in humans.Type: ApplicationFiled: February 22, 2013Publication date: January 15, 2015Applicant: Aratana Therapeutics NVInventors: Nesya Goris, Johan Neyts, Erwin Blomsma, Stefaan Wera, Jérôme Villers, Ainola Billiet, Joeri Auwerx, Veerle Debeurme, Eleonora Kiss, Chloë Swinnen
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Publication number: 20140073607Abstract: The present invention relates to compounds and compositions for use in the treatment or prevention of retroviral infections in felines, in particular cats, and to the use of said derivatives for the manufacture of a medicament for the treatment or prevention of feline leukemia virus (FeLV) infections occurring alone or together with feline immunodeficiency virus (FIV) infections in cats.Type: ApplicationFiled: May 10, 2011Publication date: March 13, 2014Applicant: OKAPI SCIENCES NVInventors: Nina Justa, Katrin Hartmann, Sylvie Daminet, Mariella Debille, Joeri Auwerx, Nesya Goris, Stefaan Wera, Erwin Blomsma, Aino Billiet, Jan Swinnen, Bert Vrancx, Veerle Debeurme, Johan Neyts
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Patent number: 7702071Abstract: A method for successively performing a powder diffraction analysis of at least two powder samples being contained in sample holding means. Use is made of an apparatus comprising:—a source of radiation being adapted to direct a radiation beam to a power sample,—a detector for detecting diffraction radiation of a powder sample,—a drive means associated with said sample holding means for effecting a movement of an irradiated powder sample during irradiation and detection. The method comprises the steps of irradiating a powder sample and detecting the diffraction radiation of the powder sample, arranging a further powder sample such that said radiation beam is directed to said further powder sample, and irradiating said further powder sample and detecting the diffraction radiation of said further sample. During irradiation and detecting of each sample the drive means effect a movement of the irradiated sample with respect to the radiation beam for the purpose of improving particle statistics.Type: GrantFiled: January 15, 2003Date of Patent: April 20, 2010Assignee: Avantium International B.V.Inventors: Erwin Blomsma, Adriaan Jan van Langevelde
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Patent number: 7608222Abstract: An assembly and method for performing parallel chemical experiments, in particular crystallisation experiments. The assembly has a main body having a first and a second face on opposite sides thereof. Multiple bores extend through said main body between said first and second face. Tubular liners are provided having openings at opposite ends thereof, each liner removably fitting in a bore in the main body. First closure means close the openings of the liners at the first face of the main body. Second closure means close the openings of the liners at the second face of the main body. The first and second closure means are fastenable to said main body, so that an experimentation chamber is defined within each liner.Type: GrantFiled: August 2, 2003Date of Patent: October 27, 2009Assignee: Avantium International B.V.Inventors: Erwin Blomsma, Adriaan Jan van Langevelde, Danny Dirk Peter Willem Stam
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Patent number: 7079621Abstract: The present invention relates to a method for performing a transmission diffraction analysis of an analyte on a support surface, wherein the method comprises: irradiating said analyte with a radiation beam generated by a source of radiation, and detecting said radiation after passing through the analyte. The method is characterised in that irradiation is performed such that the radiation beam strikes the analyte in a substantially vertical and substantially perpendicular direction. Further the present invention relates to an apparatus for performing a transmission diffraction analysis.Type: GrantFiled: October 3, 2002Date of Patent: July 18, 2006Assignee: Avantium International B.V.Inventors: Erwin Blomsma, Adriaan Jan van Langevelde
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Publication number: 20060153743Abstract: An assembly and method for performing parallel chemical experiments, in particular crystallisation experiments. The assembly has a main body having a first and a second face on opposite sides thereof. Multiple bores extend through said main body between said first and second face. Tubular liners are provided having openings at opposite ends thereof, each liner removably fitting in a bore in the main body. First closure means close the openings of the liners at the first face of the main body. Second closure means close the openings of the liners at the second face of the main body. The first and second closure means are fastenable to said main body, so that an experimentation chamber is defined within each liner.Type: ApplicationFiled: August 2, 2003Publication date: July 13, 2006Inventors: Erwin Blomsma, Adriaan Van Langevelde, Danny Dirk Stam
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Publication number: 20050069084Abstract: The present invention relates to a method for performing a transmission diffraction analysis of an analyte on a support surface, wherein the method comprises: irradiating said analyte with a radiation beam generated by a source of radiation, and detecting said radiation after passing through the analyte. The method is characterised in that irradiation is performed such that the radiation beam strikes the analyte in a substantially vertical and substantially perpendicular direction. Further the present invention relates to an apparatus for performing a transmission diffraction analysis.Type: ApplicationFiled: October 3, 2002Publication date: March 31, 2005Inventors: Erwin Blomsma, Adriaan Jan van Langevelde
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Publication number: 20050002487Abstract: A method for successively performing a powder diffraction analysis of at least two powder samples being contained in sample holding means. Use is made of an apparatus comprising:—a source of radiation being adapted to direct a radiation beam to a power sample,—a detector for detecting diffraction radiation of a powder sample,—a drive means associated with said sample holding means for effecting a movement of an irradiated powder sample during irradiation and detection. The method comprises the steps of irradiating a powder sample and detecting the diffraction radiation of the powder sample, arranging a further powder sample such that said radiation beam is directed to said further powder sample, and irradiating said further powder sample and detecting the diffraction radiation of said further sample. During irradiation and detecting of each sample the drive means effect a movement of the irradiated sample with respect to the radiation beam for the purpose of improving particle statistics.Type: ApplicationFiled: January 15, 2003Publication date: January 6, 2005Inventors: Erwin Blomsma, Adriaan van Langevelde