Patents by Inventor ERWIN F. COLUMBUS-HAGO

ERWIN F. COLUMBUS-HAGO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic hydrolysis of disaccharides and oligosaccharides using alpha-glucosidase enzymes
    Patent number: 10472657
    Abstract: A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: November 12, 2019
    Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
    Inventors: Kevin D. Nagy, Erwin F. Columbus-Hago, Jayarama K Shetty, Susan Marie Hennessey, Robert Dicosimo, Ling Hua, Rodrigo Ramirez, Zhongmei Tang, Zheyong Yu
  • Enzymatic hydrolysis of disaccharides and oligosaccharides using alpha-glucosidase enzymes
    Patent number: 10428362
    Abstract: A method is disclosed for hydrolyzing an alpha-1,5 glucosyl-fructose linkage in a saccharide (disaccharide or oligosaccharide) such as leucrose. This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase or glucoamylase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,5 glucosyl-fructose linkage of the saccharide. This method is useful for reducing the amount of leucrose in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: October 1, 2019
    Assignee: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Kevin D. Nagy, Erwin F. Columbus-Hago, Jayarama K. Shetty, Susan Marie Hennessey, Robert Dicosimo, Ling Hua, Rodrigo Ramirez, Zhongmei Tang, Zheyong Yu
  • ENZYMATIC HYDROLYSIS OF DISACCHARIDES AND OLIGOSACCHARIDES USING ALPHA-GLUCOSIDASE ENZYMES
    Publication number: 20190048376
    Abstract: A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Application
    Filed: May 24, 2018
    Publication date: February 14, 2019
    Inventors: KEVIN D. NAGY, ERWIN F. COLUMBUS-HAGO, JAYARAMA K. SHETTY, SUSAN MARIE HENNESSEY, ROBERT DICOSIMO, LING HUA, RODRIGO RAMIREZ, ZHONGMEI TANG, ZHEYONG YU
  • ENZYMATIC HYDROLYSIS OF DISACCHARIDES AND OLIGOSACCHARIDES USING ALPHA-GLUCOSIDASE ENZYMES
    Publication number: 20180273999
    Abstract: A method is disclosed for hydrolyzing an alpha-1,5 glucosyl-fructose linkage in a saccharide (disaccharide or oligosaccharide) such as leucrose. This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase or glucoamylase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,5 glucosyl-fructose linkage of the saccharide. This method is useful for reducing the amount of leucrose in a filtrate isolated from a glucan synthesis reaction, for example.
    Type: Application
    Filed: May 10, 2018
    Publication date: September 27, 2018
    Inventors: KEVIN D NAGY, ERWIN F. COLUMBUS-HAGO, JAYARAMA K. SHETTY, SUSAN MARIE HENNESSEY, ROBERT DICOSIMO, LING HUA, RODRIGO RAMIREZ, ZHONGMEI TANG, ZHEYONG YU