Patents by Inventor Erwin F. Wagner

Erwin F. Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying compounds useful in the therapy of bone disorders
    Patent number: 6653064
    Abstract: The present invention relates to a screening method for identifying a substance for the treatment of bone disorders that are associated with reduced bone mass in which the substance is tested for its ability to upregulate the expression of Fra-1 or to modulate the expression of a Fra-1 target gene in osteoblasts where the upregulation or modulation results in an increased bone formation in vivo. The identified osteoinductive compounds and DNA molecules encoding biologically active Fra-1 molecules can be used for the therapy of bone disorders characterized by a circumscribed or systemic reduction of bone mass.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: November 25, 2003
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Jochum, Jean-Pierre David, Koichi Matsuo, Erwin F. Wagner
  • Novel use of inhibitors of the epidermal growth factor receptor
    Publication number: 20020102685
    Abstract: Epidermal growth factor receptor (EGFR) inhibitor for the preparation of a medicament for the treatment of tumors whose cells proliferate as a result of a deregulated mitogenic signal transduction pathway and require the function of wildtype EGFR as a survival factor and as an inhibitor of differentiation.
    Type: Application
    Filed: July 6, 2001
    Publication date: August 1, 2002
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Maria Sibilia, Erwin F. Wagner, Axel Behrens, Alexander Fleischmann, Thomas Metz