Patents by Inventor Erwin Graef

Erwin Graef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,5-Difluoropyridines
    Patent number: 7514565
    Abstract: The invention relates to compounds of the formule
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: April 7, 2009
    Assignee: Bayer AG
    Inventors: Jürgen Stoltefuβ, Siegfried Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Maria Niewöhner, Arnold Paeβens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Dihydropyrimidines
    Publication number: 20070117812
    Abstract: The invention relates to compounds of the formulae
    Type: Application
    Filed: December 15, 2006
    Publication date: May 24, 2007
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Maria Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • Medicaments against viral diseases
    Patent number: 7074784
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: July 11, 2006
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Maria Niewohner, legal representative, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres, Ulrich Niewohner, deceased
  • Dihydropyrimidines
    Publication number: 20040167135
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) 1
    Type: Application
    Filed: February 17, 2004
    Publication date: August 26, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • Dihydropyrimidines
    Patent number: 6696451
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) The invention furthermore relates to processes for preparing the compounds of the formulae (I) and (Ia) and to their use as medicaments, in particular for the treatment and prophylaxis of hepatitis B.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: February 24, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Siegfired Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Arnold Paessens, Erwin Graef, Stefan Lettmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Medicaments against viral diseases
    Publication number: 20030232842
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Application
    Filed: March 10, 2003
    Publication date: December 18, 2003
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Ulrich Niewohner, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres
  • Medicament for viral diseases
    Publication number: 20030187028
    Abstract: Isoxazoles are highly effective anti-viral agents. Combinations of isoxazoles, dihydropyrimidines and/or lamivudine and, optionally, interferon inhibit the proliferation of HBV viruses better than conventional agents.
    Type: Application
    Filed: January 21, 2003
    Publication date: October 2, 2003
    Inventors: Michael Brands, Susanne Nikolic, Peter Eckenberg, Marcus Bauser, Johannes Kaulen, Arnold Paessens, Erwin Graef, Olaf Weber, Stefan Lottmann, Karl-Heinz Schlemmer
  • 2-heterocyclically substituted dihydropyrimidines
    Patent number: 6503913
    Abstract: The invention relates to new 2-heterocyclically substituted dihydropyrimidines, medicaments which contain these 2-heterocyclically substituted dihydropyrimidines, and a process for preparation of medicaments. The invention furthermore relates to the use of the 2-heterocyclically substituted dihydropyrimidines for the production of a medicament, in particular for the treatment of acute or chronic viral diseases, in particular for the production of a medicament for the treatment of acute or chronic hepatitis B infections.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: January 7, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegfried Goldmann, Jürgen Stoltefuss, Arnold Paessens, Erwin Graef, Stefan Lottmann
  • Use of dihydropyrimidines as medicaments, and novel substances
    Patent number: 6436943
    Abstract: The invention relates to dihydropyrimidines of the general formula and to the use of dihydropyrimidines as medicaments for the treatment and prophylaxis of hepatitis B. The invention further relates to a process for the preparation of medicaments comprising the corresponding dihydropyrimidines.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: August 20, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Siegfried Goldmann, Arnold Paessens, Erwin Graef, Stefan Lottmann
  • Medicaments for viral diseases
    Publication number: 20020082264
    Abstract: Chromanone derivatives are highly active antiviral agents. Combinations of chromanones and/or chromanols with HBV polymerase inhibitors, HBV DNA inhibitors or HBV core protein inhibitors and/or isoxazoles and, where appropriate, interferon inhibit the replication of HBV viruses better than agents disclosed previously.
    Type: Application
    Filed: August 30, 2001
    Publication date: June 27, 2002
    Inventors: Susanne Nikolic, Stephan Bartel, Michael Brands, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Karl-Heinz Schlemmer, Kerstin Henninger, Rainer Endermann, Olaf Weber, Diana Koletzki