Patents by Inventor Erwin H. Mosbach

Erwin H. Mosbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical synthesis
    Patent number: 4962099
    Abstract: A process for the production of disubstituted bile acid analogs, including the disubstituted analogs of such bile acids as, lithocholic, hyodeoxycholic, cholic, chenodeoxycholic and ursodeoxycholic acids.This invention was made in the course of work performed under a grant from the U.S. National Heart Lung and Blood Institute.
    Type: Grant
    Filed: January 5, 1989
    Date of Patent: October 9, 1990
    Assignee: Beth Israel Medical Center
    Inventors: Erwin H. Mosbach, Charles K. McSherry, Mizuho Une, Naoyuki Matoba
  • Chemical synthesis
    Patent number: 4648995
    Abstract: A compound of the formula, ##STR1## wherein R may be H or acyl; X may be H, acyl, or lower alkyl; Z may be H, hydroxy, or acyloxy; Y may be lower alkyl, aryl, alkyl substituted aryl or vinyl; and the non-toxic pharmaceutically acceptable salts thereof.This invention was made in the course of work performed under a grant from the United States National Heart Lung and Blood Institute.
    Type: Grant
    Filed: July 3, 1985
    Date of Patent: March 10, 1987
    Assignee: Beth Israel Medical Center
    Inventors: Erwin H. Mosbach, Charles K. McSherry, Syoji Kuroki
  • Chemical synthesis
    Patent number: 4545938
    Abstract: A compound of the formula, ##STR1## wherein R may be H or acyl; X may be H, acyl, or lower alkyl; Z may be H, hydroxy, or acyloxy; Y is lower alkyl; and the non-toxic pharmaceutically acceptable salts thereof.This invention was made in the course of work performed under a grant from the United States National Heart Lung and Blood Institute.
    Type: Grant
    Filed: November 2, 1983
    Date of Patent: October 8, 1985
    Assignee: Beth Israel Medical Center
    Inventors: Erwin H. Mosbach, Misuho Une, Charles K. McSherry
  • Chemical synthesis
    Patent number: 4460509
    Abstract: This invention relates to steroid compounds having a D-ring side chain structure of the formula, ##STR1## wherein R.sub.1 may be ##STR2## or --C.sub.n H.sub.2n --, wherein n is an integer from 0 to 8; Y may be S, N, or O; x is and integer of from 1 to 3; and each Z may be the same or different and is selected from the group consisting of H, OH, alkyl, aryl, aralkyl, acyloxy, cycloalkyl, substituted alkyl, substituted aryl or substituted cycloalkyl.
    Type: Grant
    Filed: August 19, 1981
    Date of Patent: July 17, 1984
    Assignee: Beth Israel Medical Center
    Inventors: Erwin H. Mosbach, Narayan K. N. Ayengar, Charles K. McSherry
  • Controlling micro-organisms
    Patent number: 4371528
    Abstract: A method of controlling microorganisms which comprises contacting said microorganisms with a small but effective amount of a compound of the formula, ##STR1## wherein R.sub.1 is H or acyl; X.sub.2 is H, OH, acyloxy, aryl, aralkyl, aryloxy, lower alkyl or lower alkoxy; X.sub.1 is H, OH or acyloxy; provided that when X.sub.2 is OH, acyloxy, lower alkoxy, or aryloxy; X.sub.1 is H or lower alkyl; and when taken together X.sub.1 and X.sub.2 are oxo (O.dbd.); Y is S, N, or O; each Z is H, OH, lower alkyl, aryl, aralkyl, substituted lower alkyl, cycloalkyl and substituted aryl; and the non-toxic pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 22, 1982
    Date of Patent: February 1, 1983
    Inventors: Erwin H. Mosbach, Charles K. McSherry, Phillip B. Hylemon