Abstract: A native, chromatographically purified ?1-AT preparation having a purity of at least 0.7 PU/mg protein and a relative plasma ?1-AT activity of at least 120% is disclosed. The ratio of active to inactive ?1-AT is higher than in plasma. Furthermore, a method of producing this preparation is disclosed, as well as the use of a carrier material, e.g. an inorganic carrier material such as hydroxylapatite for separating active ?1-AT from inactive ?1-AT.

Abstract: A native, chromatographically purified &agr;1-AT preparation having a purity of at least 0.7 PU/mg protein and a relative plasma &agr;1-AT activity of at least 120% is disclosed. The ratio of active to inactive &agr;1-AT is higher than in plasma.

Abstract: A method for removing pathogens from biological liquids and an apparatus for performing such a method, said method comprising the steps of providing a biological liquid, wherein pathogens are potentially present, in an apparatus comprising an anode and a kathode and a separation means suitable for separating said pathogens from said pharmaceutically active molecule, said separation means being positioned between said anode and said kathode, applying current between said anode and said kathode, thereby causing one of said pathogens or said pharmaceutically active molecule to pass said separation means and recovering said pharmaceutically active molecule in a form being free of said pathogens as well as an apparatus carrying out the present method.