Abstract: Formulations for pain treatment include an effective amount of liquid composition comprised of CBD, oftentimes CBG and CBN, sometimes CBC and THC, and a nominal effective amount of at least two terpenes from the group of terpenes including beta caryophyllene (CAR), ?-pinene, ?-pinene, limonene (LIM), linalool (LOL), myrcene (MYR), nerolidol (NRD), humulene (HUM), and terpinolene (TPN). For insomnia/nighttime pain: CBD, oftentimes CBG/CBN, sometimes THC, and nominal CAR, LEVI, LOL, MYR, NRD and TPN. For anxiety #1 (Calm): CBD, oftentimes CBG/CBN, sometimes THC, and nominal CAR, LEVI, LOL, MYR, and NRD. For anxiety #2 (Serenity), alter #1 and add ?-pinene, ?-pinene, HUM and TPN. For GI relief, CBD, oftentimes CBG/CBN, sometimes THC, and nominal ALL nominal CAR, ?-pinene, LEVI, LOL, MYR, and NRD. Other formulations are provided for relief of: insomnia due to pain, anxiety, etc.

Abstract: Method for dispensing a recipe includes measuring characterization data for components of a recipe. A signal representing an instruction to dispense the recipe is received at a processor operably coupled to a dispenser. In response to receiving the signal representing the instruction to dispense, an instruction set is generated based on the recipe and the characterization data. The instruction set is executed, to cause a series of delivery events of the components. Prior to each individual delivery event comprising the instruction set, a deviation, from their predetermined setpoints, is detected in a temperature and/or a pressure of the microfluidic dispenser. In response to detecting the deviation in temperature and/or pressure, the processor automatically causes an adjustment to one or more instructions from the instruction set based on the detected variation such that the amount of each component delivered more closely conforms to the amount specified in the recipe.

Abstract: Methods of treating body tissue including repairing defects in body tissue as well as augmenting body tissue. Body tissue defects are repaired by injecting a polymeric adhesive composition through an injector into the region of the defect and allowing the adhesive composition to cure to repair the defect or to form an implant that adheres to at least one surface tissue in the region of the defect. Body tissue is augmented by filling a defect void with a polymeric adhesive composition and allowing it to cure.

Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.